Fowler Mary Louise, Mahalingaiah Shruthi
Department of Obstetrics and Gynecology, Boston Medical Center, 85 E Concord St 6th Floor, Boston, MA 02118 USA.
Fertil Res Pract. 2019 Aug 1;5:8. doi: 10.1186/s40738-019-0061-0. eCollection 2019.
Approximately one-third of the world's population is infected with , and it is a leading cause of infertility in endemic countries. The global incidence of tuberculosis (TB) is growing at approximately 0.4% per year, and much faster in sub-Saharan Africa. TB causing fertility is rare in developed countries. We present a case of genital tuberculosis causing Asherman's syndrome and resultant infertility. The patient is a 34-year-old P0 who presented to care after a prolonged period of secondary amenorrhea and infertility. She underwent a hysterosalpingogram which demonstrated no free spill and a diagnostic hysteroscopy which had findings of mottled endometrium. Pathology returned positive for . The patient was treated with 9 months of antituberculous therapy. While she has not yet succeeded in becoming pregnant, the patient has started to notice cyclic spotting, indicating possible return of menses. This case highlights the importance of TB treatment and considering TB in patients who present with unexplained infertility.
世界上约三分之一的人口感染了[具体病菌名称未给出]，在流行国家，它是导致不孕的主要原因。全球结核病（TB）发病率每年约以0.4%的速度增长，在撒哈拉以南非洲增长更快。在发达国家，由结核病导致的不孕较为罕见。我们报告一例因生殖器结核导致阿谢曼综合征及继发不孕的病例。患者为34岁未育女性，因长期继发性闭经和不孕前来就诊。她接受了子宫输卵管造影，结果显示无造影剂外溢，还进行了诊断性宫腔镜检查，发现子宫内膜呈斑驳状。病理检查结果为[具体病菌名称未给出]阳性。该患者接受了9个月的抗结核治疗。虽然她尚未成功受孕，但患者已开始出现周期性点滴出血，表明月经可能恢复。该病例凸显了结核病治疗的重要性，以及对于不明原因不孕患者考虑结核病因素的重要性。
