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促进糖尿病患者中克莱恩费尔特综合征的筛查。

Facilitating screening of Klinefelter syndrome among patients with diabetes.

机构信息

Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Osaka, Japan.

出版信息

J Diabetes Investig. 2020 Mar;11(2):506-507. doi: 10.1111/jdi.13113. Epub 2019 Aug 7.

DOI:10.1111/jdi.13113
PMID:31389187
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7078131/
Abstract

Klinefelter syndrome (KS) is frequently complicated by diabetes. However, it is severely underdiagnosed due to a lack of reliable screening methods. We diagnosed two patients with KS at the Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Osaka, Japan. By comparing the patients with 39 non-KS patients with diabetes, we propose a screening tool for KS in patients with diabetes.

摘要

克莱恩费尔特综合征(KS)常伴有糖尿病。然而,由于缺乏可靠的筛查方法,该病的诊断严重不足。我们在日本大阪的武藤北里研究所糖尿病与内分泌中心诊断了两例 KS 患者。通过将这些患者与 39 例非 KS 合并糖尿病患者进行比较,我们提出了一种糖尿病患者 KS 的筛查工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9656/7078131/ef50e11d055d/JDI-11-506-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9656/7078131/ef50e11d055d/JDI-11-506-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9656/7078131/ef50e11d055d/JDI-11-506-g001.jpg

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Cell Metab. 2016 May 10;23(5):837-51. doi: 10.1016/j.cmet.2016.03.015. Epub 2016 Apr 28.
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Insulin Resistance and Inflammation in Hypogonadotropic Hypogonadism and Their Reduction After Testosterone Replacement in Men With Type 2 Diabetes.2型糖尿病男性低促性腺激素性腺功能减退患者的胰岛素抵抗与炎症及其睾酮替代治疗后的改善
Diabetes Care. 2016 Jan;39(1):82-91. doi: 10.2337/dc15-1518. Epub 2015 Nov 29.
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Screening for Klinefelter syndrome.
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Curr Opin Endocrinol Diabetes Obes. 2015 Jun;22(3):224-9. doi: 10.1097/MED.0000000000000154.
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Clinical review: Klinefelter syndrome--a clinical update.临床综述:克莱恩费尔特综合征——临床更新。
J Clin Endocrinol Metab. 2013 Jan;98(1):20-30. doi: 10.1210/jc.2012-2382. Epub 2012 Nov 1.
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Morbidity in Klinefelter syndrome: a Danish register study based on hospital discharge diagnoses.克兰费尔特综合征的发病率:一项基于医院出院诊断的丹麦登记研究。
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