Räsänen Santtu, Mäkelä Hannu, Riipinen Pirkko, Riala Kaisa, Hakko Helinä
Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland.
Department of Psychiatry, Oulu University Hospital, Oulu, Finland.
Psychiatry Investig. 2019 Aug;16(8):594-601. doi: 10.30773/pi.2019.04.20. Epub 2019 Aug 8.
To examine the association between psychiatric disorders and neoplasms.
A follow-up study of a population-based cohort of patients admitted for psychiatric care between the ages 13-17 years. The cases were patients with a follow-up diagnosis of neoplasm. The K-SADS-PL interview was used to assess DSM-IV based psychiatric diagnoses at adolescence. The treatment episodes due to neoplasms and related psychiatric disorders were extracted from the National Health Care Registers.
Of the original cohort, 6.3% of subjects had a neoplasm diagnosis. Male cases were characterized as taking snuff and females as having a fear of becoming obese. 75% of cases had smoked regularly and 47% suffered from substance misuse disorder already in adolescence. At a mean age of 22 years, the diagnoses of skin or soft tissue neoplasms were prevailing, three being malignant neoplasms of the skin, mouth or colon. Non-psychotic disorders were comorbid both two years before (26%) and after (33%) the neoplasm diagnosis.
Focus on psychiatric symptoms of patients with neoplasms may enhance their treatment outcome and quality of life.
研究精神障碍与肿瘤之间的关联。
对一个以人群为基础的队列进行随访研究，该队列中的患者年龄在13至17岁之间，因精神疾病接受治疗。病例为随访诊断为肿瘤的患者。采用K-SADS-PL访谈评估青少年基于DSM-IV的精神疾病诊断。从国家医疗保健登记册中提取因肿瘤及相关精神障碍导致的治疗记录。
在最初的队列中，6.3%的受试者被诊断患有肿瘤。男性病例的特征是吸鼻烟，女性病例的特征是害怕肥胖。75%的病例在青少年时期就经常吸烟，47%的病例已经患有物质使用障碍。在平均年龄22岁时，皮肤或软组织肿瘤的诊断最为常见，其中三例为皮肤、口腔或结肠的恶性肿瘤。在肿瘤诊断前两年（26%）和诊断后两年（33%），非精神病性障碍均为共病。
关注肿瘤患者的精神症状可能会提高他们的治疗效果和生活质量。
