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利用基因组数据重建南亚祖先的足迹。

Reconstruction of ancestral footfalls in South Asia using genomic data.

机构信息

National Institute of Biomedical Genomics, Kalyani, West Bengal 741 251, India,

出版信息

J Biosci. 2019 Jul;44(3).

PMID:31389363
Abstract

Due to its unique geographical position, juxtaposed in the middle of south-central Asia, east Asia and Southeast Asia, the South Asian Region (SAS) has repeatedly come into contact with people from adjacent regions throughout history and prehistory. The antiquity of the populations and the intricate history of admixture have shaped SAS as one of the most genetically diverse regions in the world. In this article we review our current understanding of the peopling and populations structure of SAS. We do not attempt to be exhaustive but summarize the salient conclusions that have been reached using genetic data and evaluate their robustness. We also identify the unanswered questions and suggest possible approaches that may lead to their answers.

摘要

由于其独特的地理位置,南亚地区(SAS)位于中亚、东亚和东南亚的中心地带,历史上和史前时期一直与周边地区的人们频繁接触。人口的古老性和混合的复杂历史使 SAS 成为世界上遗传多样性最丰富的地区之一。在本文中,我们回顾了我们目前对 SAS 的人口和人口结构的了解。我们并不试图面面俱到,而是总结了使用遗传数据得出的主要结论,并评估了它们的可靠性。我们还确定了未解决的问题,并提出了可能的方法来解决这些问题。

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Reconstruction of ancestral footfalls in South Asia using genomic data.利用基因组数据重建南亚祖先的足迹。
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本文引用的文献

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Reconstructing the population history of the largest tribe of India: the Dravidian speaking Gond.重构印度最大部落的人口历史:说达罗毗荼语的贡德人。
Eur J Hum Genet. 2017 Apr;25(4):493-498. doi: 10.1038/ejhg.2016.198. Epub 2017 Feb 1.
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Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation.安达曼岛人的基因组分析提供了有关古代人类向亚洲迁移和适应的见解。
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Genomic reconstruction of the history of extant populations of India reveals five distinct ancestral components and a complex structure.
对印度现存人口历史的基因组重建揭示了五个不同的祖先成分和一个复杂的结构。
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Hum Mutat. 2009 Feb;30(2):E386-94. doi: 10.1002/humu.20921.
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Annu Rev Genet. 2007;41:539-64. doi: 10.1146/annurev.genet.41.110306.130407.
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