Queensland University of Technology, Department of Statistical Science, Mathematical Sciences, Science & Engineering Faculty, Brisbane, Queensland, Australia.
ARC Centre of Excellence for Mathematical and Statistical Frontiers (ACEMS), Brisbane, Queensland, Australia.
PLoS One. 2019 Aug 7;14(8):e0218310. doi: 10.1371/journal.pone.0218310. eCollection 2019.
Floating catchment methods have recently been applied to identify priority regions for Automated External Defibrillator (AED) deployment, to aid in improving Out of Hospital Cardiac Arrest (OHCA) survival. This approach models access as a supply-to-demand ratio for each area, targeting areas with high demand and low supply for AED placement. These methods incorporate spatial covariates on OHCA occurrence, but do not provide precise AED locations, which are critical to the initial intent of such location analysis research. Exact AED locations can be determined using optimisation methods, but they do not incorporate known spatial risk factors for OHCA, such as income and demographics. Combining these two approaches would evaluate AED placement impact, describe drivers of OHCA occurrence, and identify areas that may not be appropriately covered by AED placement strategies. There are two aims in this paper. First, to develop geospatial models of OHCA that account for and display uncertainty. Second, to evaluate the AED placement methods using geospatial models of accessibility. We first identify communities with the greatest gap between demand and supply for allocating AEDs. We then use this information to evaluate models for precise AED location deployment.
Case study data set consisted of 2802 OHCA events and 719 AEDs. Spatial OHCA occurrence was described using a geospatial model, with possible spatial correlation accommodated by introducing a conditional autoregressive (CAR) prior on the municipality-level spatial random effect. This model was fit with Integrated Nested Laplacian Approximation (INLA), using covariates for population density, proportion male, proportion over 65 years, financial strength, and the proportion of land used for transport, commercial, buildings, recreation, and urban areas. Optimisation methods for AED locations were applied to find the top 100 AED placement locations. AED access was calculated for current access and 100 AED placements. Priority rankings were then given for each area based on their access score and predicted number of OHCA events.
Of the 2802 OHCA events, 64.28% occurred in rural areas, and 35.72% in urban areas. Additionally, over 70% of individuals were aged over 65. Supply of AEDs was less than demand in most areas. Priority regions for AED placement were identified, and access scores were evaluated for AED placement methodology by ranking the access scores and the predicted OHCA count. AED placement methodology placed AEDs in areas with the highest priority, but placed more AEDs in areas with more predicted OHCA events in each grid cell.
The methods in this paper incorporate OHCA spatial risk factors and OHCA coverage to identify spatial regions most in need of resources. These methods can be used to help understand how AED allocation methods affect OHCA accessibility, which is of significant practical value for communities when deciding AED placements.
最近,浮动集水区方法已被应用于识别自动体外除颤器(AED)部署的优先区域,以帮助提高院外心脏骤停(OHCA)的存活率。这种方法将访问建模为每个区域的供需比,针对 AED 放置具有高需求和低供应的区域。这些方法在 OHCA 发生时纳入了空间协变量,但没有提供精确的 AED 位置,这对于此类位置分析研究的最初意图至关重要。可以使用优化方法确定精确的 AED 位置,但它们没有纳入 OHCA 的已知空间风险因素,例如收入和人口统计学。结合这两种方法将评估 AED 放置的影响,描述 OHCA 发生的驱动因素,并确定可能未被 AED 放置策略适当覆盖的区域。本文有两个目的。首先,开发考虑和显示不确定性的 OHCA 地理空间模型。其次,使用可达性的地理空间模型评估 AED 放置方法。我们首先确定在分配 AED 方面供需差距最大的社区。然后,我们使用此信息来评估用于精确 AED 位置部署的模型。
案例研究数据集由 2802 次 OHCA 事件和 719 台 AED 组成。使用地理空间模型描述了空间 OHCA 发生情况,通过在市一级空间随机效应上引入条件自回归(CAR)先验,来考虑可能的空间相关性。使用人口密度、男性比例、65 岁以上人口比例、财务实力以及用于交通、商业、建筑物、娱乐和城市区域的土地比例等协变量,通过集成嵌套拉普拉斯近似(INLA)对该模型进行拟合。然后,应用 AED 位置优化方法来寻找前 100 个 AED 放置位置。计算了当前和 100 个 AED 放置的 AED 访问权限。然后根据其访问分数和预测的 OHCA 事件数量,为每个区域分配优先级排名。
在 2802 次 OHCA 事件中,64.28%发生在农村地区,35.72%发生在城市地区。此外,超过 70%的人年龄在 65 岁以上。大多数地区的 AED 供应都低于需求。确定了 AED 放置的优先区域,并通过对 AED 放置方法的访问分数和预测的 OHCA 计数进行排名,对 AED 放置方法的访问分数进行了评估。AED 放置方法将 AED 放置在最需要资源的区域,但在每个网格单元中,将更多的 AED 放置在预测 OHCA 事件较多的区域。
本文中的方法结合了 OHCA 空间风险因素和 OHCA 覆盖范围,以确定最需要资源的空间区域。这些方法可用于帮助了解 AED 分配方法如何影响 OHCA 的可及性,这对于社区在决定 AED 放置时具有重要的实际价值。