三例胃绒毛膜癌报告——重点关注未受影响胃黏膜的形态学变化
Report of three cases of gastric choriocarcinomas-an emphasis on morphologic changes in the non-affected gastric mucosa.
作者信息
Guzmán-López Janet C, Lino-Silva Leonardo S, Salcedo-Hernández Rosa A, Zepeda-Najar César
机构信息
Surgical Pathology, Instituto Nacional de Cancerología, Mexico City, Mexico.
Surgical Oncology, Instituto Nacional de Cancerología, Mexico City, Mexico.
出版信息
J Gastrointest Oncol. 2019 Aug;10(4):810-814. doi: 10.21037/jgo.2019.01.16.
Primary gastric choriocarcinomas (PGC) are very rare and aggressive neoplasms with a worrisome prognosis. Most cases are reported in Asia and presented in middle-aged adults with male predominance. Most cases are associated with an intestinal adenocarcinoma; however, the pathogenesis of this tumor is uncertain. No previous reports exist of the characteristics of the non-tumoral stomach in these patients, and this data that could help to clarify their pathogenesis. We presented a series of three cases of PGC in Latin American patients, emphasizing the characteristics of non-neoplastic mucosa.
原发性胃绒毛膜癌（PGC）非常罕见且具有侵袭性，预后令人担忧。大多数病例报告于亚洲，多见于中年成年人，男性居多。大多数病例与肠腺癌相关；然而，这种肿瘤的发病机制尚不确定。此前尚无关于这些患者非肿瘤性胃的特征的报道，而这些数据可能有助于阐明其发病机制。我们报告了一系列三例拉丁美洲患者的PGC病例，重点强调了非肿瘤性黏膜的特征。
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