Ammar Houssem, Said Mohamed Amine, Beltaifa Mahdi, Azri Marwa, Zgaya Rym, Majdoub Wiem, Belkacem Oussama, Gupta Rahul, Ben Hamada Habiba, Ben Ali Ali
General Surgery, Sahloul Hospital, University of Sousse, Sousse, TUN.
Obstetrics and Gynaecology, Farhat Hached Hospital, University of Sousse, Sousse, TUN.
Cureus. 2023 Jul 13;15(7):e41823. doi: 10.7759/cureus.41823. eCollection 2023 Jul.
Choriocarcinoma is a highly aggressive, malignant tumor that arises from trophoblastic cells. Although choriocarcinomas usually arise in the genital organs, they can also originate in extragenital organs, but gastrointestinal tract lesions are rare. Gastrointestinal choriocarcinoma can be primary or metastatic. Most primary gastrointestinal choriocarcinomas are associated with adenocarcinomas. We report a case of jejunal choriocarcinoma presenting with acute abdominal pain and intestinal bleeding. The patient had a very high serum beta-human chorionic gonadotropin (β-HCG) level with an isolated jejunal lesion on contrast-enhanced computed tomography of the abdomen and pelvis. The patient underwent emergency surgical resection of the jejunal lesion with good recovery. The histopathological analysis of the resected specimen confirmed the diagnosis of choriocarcinoma. However, the patient suffered from life-threatening rebleeding one month after surgery and succumbed to her illness.
绒毛膜癌是一种起源于滋养层细胞的高度侵袭性恶性肿瘤。虽然绒毛膜癌通常发生于生殖器官，但也可起源于生殖器官以外的部位，不过胃肠道病变较为罕见。胃肠道绒毛膜癌可为原发性或转移性。大多数原发性胃肠道绒毛膜癌与腺癌相关。我们报告一例以急性腹痛和肠道出血为表现的空肠绒毛膜癌病例。该患者血清β-人绒毛膜促性腺激素（β-HCG）水平极高，腹部和盆腔增强计算机断层扫描显示孤立的空肠病变。患者接受了空肠病变的急诊手术切除，恢复良好。切除标本的组织病理学分析确诊为绒毛膜癌。然而，患者术后一个月出现危及生命的再次出血，最终病逝。
