Cancer Res Treat. 2002 Dec;34(6):457-60. doi: 10.4143/crt.2002.34.6.457.
Primary gastric choriocarcinomas are very rare, and their prognosis is extremely poor. A 37-year-old woman presented with amenorrhea, vaginal spotting and severe nausea, which mimicked a pregnancy and gestational trophoblastic disease. The serum level of the beta-subunit of human chorionic gonadotrophin (beta-hCG) was significantly increased. An endoscopic biopsy of the stomach mass showed the features of a choriocarcinoma, with marked anaplasia and necrosis. Immunohistochemical staining for beta-hCG showed positive results in the choriocarcinoma. Chemotherapy for the choriocarcinoma was administered, but she died 8 months following diagnosis.
原发性胃绒毛膜癌非常罕见，预后极差。一名 37 岁女性因闭经、阴道点滴出血和严重恶心就诊，这些症状类似于妊娠和妊娠滋养细胞疾病。血清人绒毛膜促性腺激素β亚单位（β-hCG）水平显著升高。胃肿块的内镜活检显示绒毛膜癌的特征，有明显的间变和坏死。β-hCG 的免疫组织化学染色在绒毛膜癌中呈阳性结果。给予绒毛膜癌化疗，但在诊断后 8 个月死亡。
