Molaei-Langroudi Roghieh, Alizadeh Ahmad, Kazemnejad-Leili Ehsan, Monsef-Kasmaie Vahid, Moshirian Seyed-Younes
Department of Radiology, Guilan University of Medical Sciences, Rasht, Iran.
Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Bull Emerg Trauma. 2019 Jul;7(3):269-277. doi: 10.29252/beat-0703010.
To investigate the risk factors that can be proper indications for performing brain computerized tomography (CT)-scan in patients with mild and moderate traumatic brain injury (TBI) in order to avoid unnecessary exposure to radiation, saving on costs as well as time wasted in emergency wards.
Data of patients with mild traumatic brain injury (TBI) referring to Emergency Department with age ≥2 years and primary GCS of 13-15 were examined including focal neurological deficit, anisocoria, skull fracture, multiple trauma, superior injury of clavicle, decreased consciousness, and amnesia. Brain CT-scan was performed in all the patients. Kappa Coefficient was used to determine the ratio of agreement of the CT indications (+ and ⎼) and multiple logistic regression to determine the relative odds of positive CTs.
Overall we included 610 patients. One-hundred and one patients (16.5%) had positive and 509 (83.5%) had negative CT findings. Of positive CTs, the highest percentage was dedicated to high-energy mechanism of trauma. High-energy trauma mechanism (OR=1.056, 95% CI, OR, 1.03-1.04, P<0.001), superior injury of clavicle (OR=1.07, 95% CI, OR, 1.03-1.1, P<0.001) and moderate to severe headache (OR=1.04, 95% CI, OR, 1.02-1.05, P<0.001) were positive predictors of CT findings. The combined mean of positive symptoms equaled 0.29 ± 0.64 in negative CTs, but 5.13 ± 2.4 in positive CTs, showing a significant difference. (P<0.001).
Abnormal positive brain CT in victims with mild TBI is predictable if one or several risk factors are taken into account such as moderate to severe headache, decreased consciousness, skull fracture, high-energy trauma mechanism, superior injury of clavicle and GCS of 13-14. The more the symptoms, the more likely the positive CT results would be.
探讨对于轻度和中度创伤性脑损伤(TBI)患者,哪些风险因素可作为进行脑部计算机断层扫描(CT)的恰当指征,以避免不必要的辐射暴露,节省费用以及减少在急诊科浪费的时间。
对年龄≥2岁、初次格拉斯哥昏迷量表(GCS)评分为13 - 15分的轻度创伤性脑损伤(TBI)急诊患者的数据进行检查,包括局灶性神经功能缺损、瞳孔不等大、颅骨骨折、多发伤、锁骨上损伤、意识减退和失忆。所有患者均进行了脑部CT扫描。使用kappa系数确定CT指征(阳性和阴性)的一致率,并采用多因素logistic回归确定CT阳性的相对比值比。
总共纳入610例患者。101例患者(16.5%)CT结果为阳性,509例(83.5%)为阴性。在阳性CT结果中,因高能创伤机制导致的比例最高。高能创伤机制(OR = 1.056,95%可信区间,OR,1.03 - 1.04,P < 0.001)、锁骨上损伤(OR = 1.07,95%可信区间,OR,1.03 - 1.1,P < 0.001)和中重度头痛(OR = 1.04,95%可信区间,OR,1.02 - 1.05,P < 0.001)是CT结果阳性的预测因素。阴性CT结果中阳性症状的合并均值为0.29±0.64,但阳性CT结果中为5.13±2.4,差异有统计学意义(P < 0.001)。
如果考虑到一个或几个风险因素,如中重度头痛、意识减退、颅骨骨折、高能创伤机制、锁骨上损伤以及GCS评分为13 - 14分,轻度TBI患者脑部CT出现异常阳性结果是可预测的。症状越多,CT结果为阳性的可能性越大。