Aix-Marseille University, CNRS, CRMBM, Marseille, France.
APHM, Hôpital Universitaire Timone, CEMEREM, Marseille, France.
NMR Biomed. 2019 Nov;32(11):e4142. doi: 10.1002/nbm.4142. Epub 2019 Aug 8.
The recently-proposed MP2RAGE sequence was purposely optimized for cervical spinal cord imaging at 3T. Sequence parameters were chosen to optimize gray/white matter T contrast with sub-millimetric resolution and scan-time < 10 min while preserving reliable T determination with minimal B variation effects within a range of values compatible with pathologies and surrounding structures. Results showed good agreements with IR-based measurements, high MP2RAGE-based T reproducibility and preliminary evidences of age- and tract-related T variations in the healthy spinal cord.
最近提出的 MP2RAGE 序列是专门针对 3T 颈椎脊髓成像优化的。选择序列参数的目的是优化具有亚毫米分辨率的灰/白质 T 对比度，扫描时间<10 分钟，同时在与病变和周围结构兼容的范围内，通过最小的 B 变化效果来可靠地确定 T 值。结果与基于 IR 的测量值具有很好的一致性，MP2RAGE 基于 T 的重现性很高，并且在健康的脊髓中存在与年龄和束相关的 T 变化的初步证据。
