Laboratory of Food Chemistry, Wageningen University, P.O. Box 17, 6700 AA Wageningen, the Netherlands; Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
Groningen Institute for Evolutionary Life Science, University of Groningen, Groningen, the Netherlands.
Int J Biol Macromol. 2019 Nov 1;140:515-521. doi: 10.1016/j.ijbiomac.2019.08.032. Epub 2019 Aug 5.
Consumption of non-starch polysaccharides (NSP) is associated with reduced risk of obesity. This study aimed to compare the effects of cereals (oats) and legumes (soybean), rich in different classes of NSP, on appetite regulation and fat accumulation in rats. Soy pectin fermented more efficient than cereal arabinoxylan in rats. Soy pectin and oat β-glucan were utilized mainly in the caecum of rats. Only small amount of maltodextrin, cello-oligosaccharides and xylo-oligosaccharides were detected in the digesta. Caecal fermentation of soy pectin produced significantly higher concentration of short chain fatty acids (SCFAs) compared to the control. Retroperitoneal (RP) fat-pad weight was significantly lower for rats fed with soybean meal enriched diet than for controls. An inverse correlation between rat RP fat-pad weight and concentration (and proportion) of butyrate was observed. Consumption of soy pectin and oat β-glucan enriched foods to produce targeted SCFAs in vivo could be a potential strategy to lower fat mass accumulation and a potential tool to manage obesity.
非淀粉多糖（NSP）的消耗与肥胖风险降低有关。本研究旨在比较富含不同 NSP 类别的谷物（燕麦）和豆类（大豆）对大鼠食欲调节和脂肪积累的影响。大豆果胶在大鼠体内比谷物阿拉伯木聚糖发酵效率更高。大豆果胶和燕麦 β-葡聚糖主要在大鼠盲肠中被利用。在消化物中仅检测到少量的麦芽糊精、纤维二糖寡糖和木二糖寡糖。与对照组相比，大豆果胶的盲肠发酵产生了显著更高浓度的短链脂肪酸（SCFA）。与对照组相比，用富含大豆粉的饮食喂养的大鼠的腹膜后（RP）脂肪垫重量显著降低。观察到大鼠 RP 脂肪垫重量与丁酸盐的浓度（和比例）呈负相关。在体内消耗富含大豆果胶和燕麦 β-葡聚糖的食物以产生靶向 SCFA，可能是降低脂肪量积累的潜在策略，也是管理肥胖的潜在工具。
