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一种可生物降解镁合金支架的数值腐蚀疲劳模型。

A numerical corrosion-fatigue model for biodegradable Mg alloy stents.

机构信息

Beijing Advanced Innovation Center for Materials Genome Engineering & Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China.

Schlumberger Technology Corporation, Houston, TX 77054, USA.

出版信息

Acta Biomater. 2019 Oct 1;97:671-680. doi: 10.1016/j.actbio.2019.08.004. Epub 2019 Aug 5.

Abstract

Biodegradable magnesium alloys have attracted research interest as matrix materials for next-generation absorbable metallic coronary stents. Subject to cyclic stresses, magnesium alloy stents (MAS) are prone to premature failures caused by corrosion fatigue damage. This work aimed to develop a numerical continuum damage mechanics model, implemented with the finite element method, which can account for the corrosion fatigue of Mg alloys and the applications in coronary stents. The parameters in the resulting phenomenological model were calibrated using our previous experimental data of HP-Mg and WE43 alloy and then applied in assessing the performance of the MAS. The results indicated that it was valid to predict the degradation rate, the damage-induced reduction of the radial stiffness, and the critical location of the MAS. Furthermore, this model and the numerical procedure can be easily adapted for other biodegradable alloy systems, for instance, Fe and Zn, and used to achieve the optimal degradation rate while improving fatigue endurance. STATEMENT OF SIGNIFICANCE: Subject to cyclic stresses, magnesium alloy stents are prone to premature failures caused by corrosion fatigue damage. This work aimed to develop a numerical continuum damage mechanics model, implemented with the finite element method, which can account for the corrosion fatigue of Mg alloys and the applications in coronary stents. The results indicated that it was valid to predict the degradation rate, damage-induced reduction of the radial stiffness, and the critical location of the Mg alloy stent; therefore, these stents can be easily adapted to other biodegradable alloy systems such as Fe and Zn.

摘要

可生物降解镁合金作为下一代可吸收金属冠状动脉支架的基体材料引起了研究兴趣。镁合金支架(MAS)在循环应力作用下容易发生腐蚀疲劳损伤导致早期失效。本工作旨在开发一个数值连续损伤力学模型,采用有限元方法实现,能够考虑镁合金的腐蚀疲劳及其在冠状动脉支架中的应用。所得唯象模型中的参数采用我们之前的 HP-Mg 和 WE43 合金的实验数据进行标定,然后用于评估 MAS 的性能。结果表明,该模型能够有效地预测 MAS 的降解速率、损伤引起的径向刚度降低以及关键位置。此外,该模型和数值程序可以很容易地应用于其他可生物降解的合金体系,例如 Fe 和 Zn,从而实现最佳降解速率的同时提高疲劳耐久性。

意义陈述

在循环应力作用下,镁合金支架容易发生腐蚀疲劳损伤导致早期失效。本工作旨在开发一个数值连续损伤力学模型,采用有限元方法实现,能够考虑镁合金的腐蚀疲劳及其在冠状动脉支架中的应用。结果表明,该模型能够有效地预测 MAS 的降解速率、损伤引起的径向刚度降低以及关键位置;因此,这些支架可以很容易地适应其他可生物降解的合金体系,例如 Fe 和 Zn。

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