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即将出现的阻塞性睡眠呼吸暂停综合管理方案:西班牙睡眠网络概述。

Upcoming Scenarios for the Comprehensive Management of Obstructive Sleep Apnea: An Overview of the Spanish Sleep Network.

机构信息

Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain; Medicine Department, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.

Pneumology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.

出版信息

Arch Bronconeumol (Engl Ed). 2020 Jan;56(1):35-41. doi: 10.1016/j.arbres.2019.05.017. Epub 2019 Aug 5.

DOI:10.1016/j.arbres.2019.05.017
PMID:31395388
Abstract

Sleep is considered an essential part of life and plays a vital role in good health and well-being. Equally important as a balanced diet and adequate exercise, quality and quantity of sleep are essential for maintaining good health and quality of life. Sleep-disordered breathing is one of the most prevalent conditions that compromises the quality and duration of sleep, with obstructive sleep apnea (OSA) being the most prevalent disorder among these conditions. OSA is a chronic and highly prevalent disease that is considered to be a true public health problem. OSA has been associated with increased cardiovascular, neurocognitive, metabolic and overall mortality risks, and its management is a challenge facing the health care system. To establish the main future lines of research in sleep respiratory medicine, the Spanish Sleep Network (SSN) promoted the 1st World Café experts' meeting. The overall vision was established by consensus as "Sleep as promoter of health and the social impact of sleep disturbances". Under this leitmotiv and given that OSA is the most prevalent sleep disorder, five research lines were established to develop a new comprehensive approach for OSA management: (1) an integrated network for the comprehensive management of OSA; (2) the biological impact of OSA on comorbidities with high mortality, namely, cardiovascular and metabolic diseases, neurocognitive diseases and cancer; (3) Big Data Analysis for the identification of OSA phenotypes; (4) personalized medicine in OSA; and (5) OSA in children: current needs and future perspectives.

摘要

睡眠被认为是生命的重要组成部分,对健康和幸福起着至关重要的作用。与均衡饮食和充足运动同等重要的是,睡眠的质量和数量对于维持良好的健康和生活质量至关重要。睡眠呼吸障碍是最常见的影响睡眠质量和持续时间的病症之一,其中阻塞性睡眠呼吸暂停(OSA)是这些病症中最常见的障碍。OSA 是一种慢性且高发的疾病,被认为是一个真正的公共卫生问题。OSA 与心血管、神经认知、代谢和总体死亡率风险增加有关,其管理是医疗保健系统面临的挑战。为了确定睡眠呼吸医学研究的主要未来方向,西班牙睡眠网络(SSN)促进了第 1 届世界咖啡专家会议。总体愿景是通过共识确定为“睡眠促进健康以及睡眠障碍的社会影响”。在这个主题下,并且鉴于 OSA 是最常见的睡眠障碍,确定了五条研究路线来制定 OSA 管理的新综合方法:(1)OSA 综合管理的综合网络;(2)OSA 对高死亡率合并症的生物学影响,即心血管和代谢疾病、神经认知疾病和癌症;(3)用于识别 OSA 表型的大数据分析;(4)OSA 中的个性化医学;以及(5)儿童 OSA:当前需求和未来展望。

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Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome.急性冠状动脉综合征患者的呼吸多导记录仪模式与心血管事件复发风险
Front Med (Lausanne). 2022 Jun 27;9:870906. doi: 10.3389/fmed.2022.870906. eCollection 2022.
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Endogenous controls and microRNA profile in female patients with obstructive sleep apnea.女性阻塞性睡眠呼吸暂停患者的内源性调控和 microRNA 谱。
Sci Rep. 2022 Feb 3;12(1):1916. doi: 10.1038/s41598-022-05782-y.
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Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle.阻塞性睡眠呼吸暂停:针对颏舌肌的新兴治疗方法。
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