• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Optimal Detection of Subtle Gadolinium Leakage in CSF with Heavily T2-Weighted Fluid-Attenuated Inversion Recovery Imaging.采用重 T2 加权液体衰减反转恢复成像技术对脑脊液中细微钆渗漏的最佳检测。
AJNR Am J Neuroradiol. 2019 Sep;40(9):1481-1483. doi: 10.3174/ajnr.A6145. Epub 2019 Aug 8.
2
Pericortical Enhancement on Delayed Postgadolinium Fluid-Attenuated Inversion Recovery Images in Normal Aging, Mild Cognitive Impairment, and Alzheimer Disease.正常衰老、轻度认知障碍和阿尔茨海默病患者延迟钆增强液体衰减反转恢复图像上的皮质周围增强。
AJNR Am J Neuroradiol. 2017 Sep;38(9):1742-1747. doi: 10.3174/ajnr.A5273. Epub 2017 Jul 6.
3
Abrogation of fluid suppression in intracranial postcontrast fluid-attenuated inversion recovery magnetic resonance imaging: A clinical and phantom study.颅内增强后液体衰减反转恢复磁共振成像中液体抑制的消除：一项临床与模型研究。
Vet Radiol Ultrasound. 2018 Jul;59(4):432-443. doi: 10.1111/vru.12605. Epub 2018 Feb 8.
4
Relationship between contrast enhancement on fluid-attenuated inversion recovery MR sequences and signal intensity on T2-weighted MR images: visual evaluation of brain tumors.液体衰减反转恢复磁共振序列上的对比增强与T2加权磁共振图像上的信号强度之间的关系：脑肿瘤的视觉评估
J Magn Reson Imaging. 2005 Jun;21(6):694-700. doi: 10.1002/jmri.20331.
5
Brain: gadolinium-enhanced fast fluid-attenuated inversion-recovery MR imaging.脑：钆增强快速液体衰减反转恢复磁共振成像。
Radiology. 1999 Apr;211(1):257-63. doi: 10.1148/radiology.211.1.r99mr25257.
6
Cerebrospinal fluid changes after intravenous injection of gadolinium chelate: assessment by FLAIR MR imaging.静脉注射钆螯合物后脑脊液的变化：通过液体衰减反转恢复序列磁共振成像评估
Eur Radiol. 2003 Mar;13(3):592-7. doi: 10.1007/s00330-002-1546-4. Epub 2002 Jul 13.
7
In vitro investigation of poor cerebrospinal fluid suppression on fluid-attenuated inversion recovery images in the presence of a gadolinium-based contrast agent.在钆基造影剂存在的情况下，对液体衰减反转恢复图像上脑脊液抑制不佳的体外研究。
Magn Reson Med. 2008 Jul;60(1):220-3. doi: 10.1002/mrm.21619.
8
Asymmetrical Gadolinium Leakage in Ocular Structures in Stroke Due to Internal Carotid Artery Stenosis or Occlusion.颈内动脉狭窄或闭塞所致中风患者眼部结构中钆的不对称渗漏
Clin Neuroradiol. 2020 Jun;30(2):221-228. doi: 10.1007/s00062-018-0754-5. Epub 2018 Dec 28.
9
Age-related changes in the distribution of intravenously administered gadolinium-based contrast agents leaked into the cerebrospinal fluid in patients with suspected endolymphatic hydrops.疑似内淋巴积水患者静脉注射钆基造影剂漏入脑脊液后的分布与年龄的相关性变化。
Jpn J Radiol. 2021 May;39(5):433-441. doi: 10.1007/s11604-020-01079-0. Epub 2021 Jan 1.
10
Contrast Enhancement of the Normal Infundibular Recess Using Heavily T2-weighted 3D FLAIR.使用重度 T2 加权 3D FLAIR 增强正常漏斗隐窝的对比度。
Magn Reson Med Sci. 2022 Jul 1;21(3):469-476. doi: 10.2463/mrms.mp.2021-0021. Epub 2021 May 13.

引用本文的文献

1
Hyperintense acute reperfusion marker and gadolinium leakage in ocular structures in stroke: a systematic review.急性再灌注高信号标志物与脑卒中眼部结构钆渗漏：一项系统评价
Neuroradiology. 2025 May 13. doi: 10.1007/s00234-025-03646-6.
2
CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review.对比剂增强后液体衰减反转恢复序列图像上的脑脊液强化：一项系统评价
Neuroimage Clin. 2020;28:102456. doi: 10.1016/j.nicl.2020.102456. Epub 2020 Oct 2.
3
Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent.确认静脉内给予钆基造影剂后，大脑皮层静脉周围的造影剂漏入脑脊液与年龄有关。
Magn Reson Med Sci. 2020 Dec 1;19(4):375-381. doi: 10.2463/mrms.mp.2019-0182. Epub 2020 Feb 6.

本文引用的文献

1
Pericortical Enhancement on Delayed Postgadolinium Fluid-Attenuated Inversion Recovery Images in Normal Aging, Mild Cognitive Impairment, and Alzheimer Disease.正常衰老、轻度认知障碍和阿尔茨海默病患者延迟钆增强液体衰减反转恢复图像上的皮质周围增强。
AJNR Am J Neuroradiol. 2017 Sep;38(9):1742-1747. doi: 10.3174/ajnr.A5273. Epub 2017 Jul 6.
2
Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: A retrospective, pilot, observational longitudinal study.脑脊髓膜对比增强与 MS 皮质萎缩进展相关：一项回顾性、前瞻性、观察性纵向研究。
Mult Scler. 2017 Sep;23(10):1336-1345. doi: 10.1177/1352458516678083. Epub 2016 Nov 4.
3
Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis.基于钆的磁共振成像对多发性硬化软脑膜炎症的特征分析
Neurology. 2015 Jul 7;85(1):18-28. doi: 10.1212/WNL.0000000000001587. Epub 2015 Apr 17.
4
Investigation of leptomeningeal enhancement in MS: a postcontrast FLAIR MRI study.MS 患者软脑膜增强的研究：一项对比增强 FLAIR MRI 研究。
Neurology. 2015 Feb 24;84(8):770-5. doi: 10.1212/WNL.0000000000001286. Epub 2015 Jan 23.
5
Blood-brain barrier disruption after cardiac surgery.心脏手术后的血脑屏障破坏。
AJNR Am J Neuroradiol. 2013 Mar;34(3):518-23. doi: 10.3174/ajnr.A3251. Epub 2012 Aug 23.
6
Hyperacute injury marker (HARM) in primary hemorrhage: a distinct form of CNS barrier disruption.原发性出血中的超急性损伤标志物（HARM）：一种中枢神经系统屏障破坏的独特形式。
Neurology. 2011 Nov 8;77(19):1725-8. doi: 10.1212/WNL.0b013e318236ef46. Epub 2011 Oct 26.
7
The hyperintense acute reperfusion marker on fluid-attenuated inversion recovery magnetic resonance imaging is caused by gadolinium in the cerebrospinal fluid.FLAIR 磁共振成像上的急性再灌注高亮信号标记物是由脑脊液中的钆导致的。
Stroke. 2012 Jan;43(1):259-61. doi: 10.1161/STROKEAHA.111.632356. Epub 2011 Oct 6.
8
Early blood-brain barrier disruption in human focal brain ischemia.人类局灶性脑缺血中血脑屏障的早期破坏
Ann Neurol. 2004 Oct;56(4):468-77. doi: 10.1002/ana.20199.

采用重 T2 加权液体衰减反转恢复成像技术对脑脊液中细微钆渗漏的最佳检测。

Optimal Detection of Subtle Gadolinium Leakage in CSF with Heavily T2-Weighted Fluid-Attenuated Inversion Recovery Imaging.

机构信息

From the Department of Psychiatry and Neuropsychology (W.M.F., R.W.v.H., H.I.L.J., F.R.V.), Maastricht University, School for Mental Health and Neuroscience, Alzheimer Centrum Limburg, Maastricht, the Netherlands.

Department of Radiology and Nuclear Medicine (W.M.F., W.M.P., J.F.A,J., W.H.B.), Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, the Netherlands.

出版信息

AJNR Am J Neuroradiol. 2019 Sep;40(9):1481-1483. doi: 10.3174/ajnr.A6145. Epub 2019 Aug 8.

DOI:10.3174/ajnr.A6145
PMID:31395665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7048436/
Abstract

Pericortical enhancement on postcontrast FLAIR images is a marker for subtle leptomeningeal blood-brain barrier leakage. We explored the optimal FLAIR sequence parameters for the detection of low gadolinium concentrations within the CSF. On the basis of phantom experiments and human in vivo data, we showed that detection of subtle pericortical enhancement can be facilitated by using a relatively long TE. Future studies should choose their FLAIR sequence parameters carefully when assessing pericortical enhancement due to subtle blood-brain barrier leakage.

摘要

皮质周围增强在对比后 FLAIR 图像上是细微脑膜血脑屏障渗漏的标志物。我们探索了最佳的 FLAIR 序列参数，以检测 CSF 中的低钆浓度。基于体模实验和人体体内数据，我们表明使用相对较长的 TE 可以促进细微皮质周围增强的检测。未来的研究在评估由于细微血脑屏障渗漏导致的皮质周围增强时，应该仔细选择 FLAIR 序列参数。