A synthetic adjuvant effective in inducing antitumor immunity.
作者信息
Kataoka T, Tokunaga T
机构信息
Department of Cellular Immunology, National Institute of Health, Tokyo.
出版信息
Jpn J Cancer Res. 1988 Jul;79(7):817-20. doi: 10.1111/j.1349-7006.1988.tb00042.x.
Abstract
Guinea pigs which were injected repeatedly with a mixture of a 3M KCl extract of line 10 tumor and 6-O-(2-tetradecyl-hexadecanoyl)-muramyl-dipeptide (B30-MDP) rejected a tumor graft of line 10. Such an adjuvant effect of B30-MDP was also demonstrated when X-ray-treated line 10 cells were mixed with B30-MDP dissolved in phosphate-buffered saline and inoculated into the animals.
摘要
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