Department of Pediatrics, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.
Department of General Surgery, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.
Neurourol Urodyn. 2019 Nov;38(8):2288-2295. doi: 10.1002/nau.24136. Epub 2019 Aug 8.
We performed a systematic review and meta-analysis to evaluate the efficacy of electrical stimulation (ES) in treating children with nocturnal enuresis (NE).
Randomized controlled trials (RCTs) of the use of ES for the treatment of NE in children were searched using EMBASE, MEDLINE, and the Cochrane Controlled Trials Register. The references of related articles were also searched. The systematic review was carried out using the Preferred Reporting Items for Systematic Reviews and Meta-analyses.
Four RCTs involving 171 patients were studied. We found that there was statistically significant difference in the wet nights per week (mean difference [MD], -0.70; 95% confidence interval [CI], -0.89 to -0.51; P < .00001), the number of patients with clinical response (MD, 26.88; 95% CI, 11.16 to 64.74; P < .00001), and bladder capacity (MD, -0.70; 95% CI -0.89 to -0.51; P < .00001) in the ES group compared with the placebo group with the exception of maximum voided volume (MVV) (MD, 19.48; 95% CI, -9.18 to 48.14; P = .18).
The study provides a significant improvement in statistics in the wet nights per week, the number of patients with clinical response and bladder capacity for children with NE compared with the placebo group with the exception of MVV.
我们进行了系统评价和荟萃分析，以评估电刺激（ES）治疗儿童夜间遗尿（NE）的疗效。
使用 EMBASE、MEDLINE 和 Cochrane 对照试验登记处搜索 ES 治疗儿童 NE 的随机对照试验（RCT）。还搜索了相关文章的参考文献。系统评价使用系统评价和荟萃分析的首选报告项目进行。
研究了 4 项涉及 171 名患者的 RCT。我们发现，每周湿夜数（均数差 [MD]，-0.70；95%置信区间 [CI]，-0.89 至 -0.51；P<0.00001）、有临床反应的患者数（MD，26.88；95%CI，11.16 至 64.74；P<0.00001）和膀胱容量（MD，-0.70；95%CI，-0.89 至 -0.51；P<0.00001）在 ES 组与安慰剂组之间存在统计学显著差异，但最大排尿量（MVV）除外（MD，19.48；95%CI，-9.18 至 48.14；P=0.18）。
与安慰剂组相比，该研究为 NE 患儿每周湿夜数、有临床反应的患者数和膀胱容量提供了统计学上的显著改善，但 MVV 除外。
