Faculdade de Ciências Médicas de Santos, Centro Universitário Lusíada, São Paulo, Brazil.
Urology Department, Faculdade de Medicina Do ABC, Centro Universitário Saúde ABC, Santo André, São Paulo, Brazil.
J Pediatr Urol. 2021 Jun;17(3):295-301. doi: 10.1016/j.jpurol.2021.02.012. Epub 2021 Feb 18.
To analyze the effect of electrical nerve stimulation on urinary symptoms in pediatric patients with monosymptomatic primary enuresis refractory to conventional treatment.
Three databases (Medline, Embase, and Cochrane) were searched and 160 studies were identified by July 15, 2020. After establishing and applying the inclusion and exclusion criteria, a step-by-step analysis was performed using the title, abstract and full text. The Cochrane Collaboration Tool was then used to analyze the biases of the selected studies.
Of the 160 articles found, 03 were selected for this systematic review. In 02 studies there was a significant reduction in the number of wet nights/week after electrical nerve stimulation. Urodynamic pattern was evaluated in 01 study, with improvement of maximum cystometric capacity in the intervention group. About maximum voided volume, there was no improvement in 01 study, but in other, there was increase in the intervention group.
Electrical nerve stimulation might promote improvement in partial and total response scores over the number of dry nights, with no improvement in urodynamic parameters, and could be considered as an feasible option in the management of refractory monosymptomatic primary enuresis. However, it is worth emphasizing the need to conduct more RCTs with a larger sample for better evaluation of the role of neurostimulation.
分析电神经刺激对常规治疗无效的单症状性原发性遗尿症患儿排尿症状的影响。
检索了 3 个数据库（Medline、Embase 和 Cochrane），并于 2020 年 7 月 15 日确定了 160 项研究。在建立并应用纳入和排除标准后，使用标题、摘要和全文进行了逐步分析。然后使用 Cochrane 协作工具分析了所选研究的偏倚。
在发现的 160 篇文章中，有 03 篇被选入本系统评价。在 02 项研究中，电神经刺激后湿夜/周的数量明显减少。在 01 项研究中评估了尿动力学模式，干预组最大膀胱容量增加。关于最大排尿量，01 项研究无改善，但另一项研究干预组增加。
电神经刺激可能会促进部分和总反应评分在夜间干燥次数上的改善，而对尿动力学参数没有改善，可以作为治疗难治性单症状性原发性遗尿症的可行选择。然而，值得强调的是，需要进行更多的 RCT 研究，以更大的样本量更好地评估神经刺激的作用。
