Zhu Dan, Gao Cen, Zhong Yuan-Ming
Department of TCM, Affilated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Department of Acupuncture and Moxibustion, First Affilated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province.
Zhongguo Zhen Jiu. 2019 Aug 12;39(8):837-40. doi: 10.13703/j.0255-2930.2019.08.010.
To compare the therapeutic effect between acupuncture and hyaluronic acid sodium eye drops for dry eye syndrome.
A total of 60 patients with dry eye were randomized into an acupuncture group and a western medication group, 30 cases in each one. In the acupuncture group, acupoints around the eyes, abdomen and limbs were selected, such as Jingming (BL 1), Cuanzhu (BL 2), Fengchi (GB 20), Taiyang (EX-HN 5), Guanyuan (CV 4), Qihai (CV 6) and Hegu (LI 4), once 2 days for 1 month, 15 times in total. In the western medication group, hyaluronic acid sodium eye drops was applied, 3 times a day, one drop every time, for 1 month. The tear meniscus height (TMH), tear break-up time (BUT) and conjunctival congestion scores were observed before and after treatment in the two groups, and the clinical effects of the two groups were compared.
The total effective rate in the acupuncture group was 68.3% (41/60), which was superior to 30.0% (18/60) in the western medication group (<0.05). Compared before treatment, the TMH was increased, BUT was prolonged and conjunctival congestion score was reduced after treatment in the acupuncture group (<0.05, <0.01). After treatment, the TMH and BUT in the acupuncture group were higher (<0.05, <0.01), and the conjunctival congestion score was lower than those in the western medication group (<0.05).
The therapeutic effect of acupuncture is superior to hyaluronic acid sodium eye drops. Acupuncture can promote lacrimal gland secretion and increase the tear film stability.
比较针刺与透明质酸钠滴眼液治疗干眼综合征的疗效。
将60例干眼患者随机分为针刺组和西药组,每组30例。针刺组选取眼周、腹部及四肢穴位,如睛明(BL 1)、攒竹(BL 2)、风池(GB 20)、太阳(EX-HN 5)、关元(CV 4)、气海(CV 6)和合谷(LI 4),每2天治疗1次,共治疗1个月,总计15次。西药组应用透明质酸钠滴眼液,每日3次,每次1滴,治疗1个月。观察两组治疗前后的泪膜高度(TMH)、泪膜破裂时间(BUT)及结膜充血评分,并比较两组的临床疗效。
针刺组总有效率为68.3%(41/60),优于西药组的30.0%(18/60)(P<0.05)。针刺组治疗后与治疗前比较,TMH升高,BUT延长,结膜充血评分降低(P<0.05,P<0.01)。治疗后,针刺组的TMH和BUT高于西药组(P<0.05,P<0.01),结膜充血评分低于西药组(P<0.05)。
针刺的治疗效果优于透明质酸钠滴眼液。针刺可促进泪腺分泌,提高泪膜稳定性。