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使用托拉塞米和螺内酯后出现低钾性四肢瘫。

Hypokalaemic quadriparesis following torsemide and spironolactone use.

作者信息

Kaur Upinder, Chakrabarti Sankha Shubhra, Choudhury Ashis Kumar, Gambhir Indrajeet Singh

机构信息

Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

Natl Med J India. 2018 Nov-Dec;31(6):347-348. doi: 10.4103/0970-258X.262913.

DOI:10.4103/0970-258X.262913
PMID:31397368
Abstract

Mild hypokalaemia is a common electrolyte abnormality following therapeutic doses of diuretics such as torsemide. If undiagnosed and untreated, hypokalaemia progresses and smooth muscle, skeletal muscle and the heart are affected. Potassium-sparing diuretics such as spironolactone are commonly added to loop diuretics to prevent symptomatic hypokalaemia. We present a patient with moderate hypokal-aemia associated with the use of torsemide and spironolactone, resulting in quadriparesis, hospitalization and electrophysio-logical abnormalities.

摘要

轻度低钾血症是使用托拉塞米等治疗剂量利尿剂后常见的电解质异常情况。如果未被诊断和治疗,低钾血症会进展并影响平滑肌、骨骼肌和心脏。常将螺内酯等保钾利尿剂添加到袢利尿剂中以预防症状性低钾血症。我们报告了一名与使用托拉塞米和螺内酯相关的中度低钾血症患者,该患者出现四肢瘫痪、住院及电生理异常。

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Natl Med J India. 2018 Nov-Dec;31(6):347-348. doi: 10.4103/0970-258X.262913.
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