甲基化介导的调控：在 mRNAs 上添加 mAm。
Manipulation by Methylation: Garnishing mRNAs with mAm.
机构信息
Cecil H. and Ida Green Center for Reproductive Biology Sciences and Division of Basic Reproductive Biology Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biophysics, Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Cecil H. and Ida Green Center for Reproductive Biology Sciences and Division of Basic Reproductive Biology Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
出版信息
Mol Cell. 2019 Aug 8;75(3):417-418. doi: 10.1016/j.molcel.2019.07.019.
Abstract
In two recent publications in Molecular Cell,Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map mAm modification sites transcriptome-wide and demonstrate that mAm can repress translation while increasing the stability of a subset of low-abundance transcripts.
摘要
在最近发表在《Molecular Cell》上的两篇论文中，Boulias 等人（2019 年）和 Sendinc 等人（2019 年）采用互补的方法对 mAm 修饰位点进行全转录组作图，并证明 mAm 可以在抑制翻译的同时增加一部分低丰度转录本的稳定性。
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