Hussein Mogahed Ismail Hassan
Department of Internal Medicine, Faculty of Medicine, University of Gezira, Wad Medani City, Sudan.
Oxf Med Case Reports. 2019 Aug 1;2019(8). doi: 10.1093/omcr/omz073.
The combination of schistosomiasis and pulmonary hypertension (PH) was always recognized as a very rare one; in medical literature, PH is considered as a manifestation of hepatosplenic schistosomiasis but not a manifestation of schistosomal infection until recently. Only 18.5% of patients that have a documented hepatosplenic schistosomiasis were found with PH. Schistosomiasis rarely causes PH without evident hepatosplenic manifestations. Here, we are reporting a case of a patient whose first clinical presentation was features of PH. We use this case as an opportunity to outline pathological mechanisms, causes and classification of PH. A structured and thorough workup for PH is emphasized. It is important to exclude all other secondary causes to be able to diagnose primary PH especially in the absence of a positive family history and advanced diagnostic technology.
血吸虫病与肺动脉高压（PH）的合并情况一直被认为非常罕见；在医学文献中，直到最近，PH都被视为肝脾型血吸虫病的一种表现，而非血吸虫感染的表现。在有记录的肝脾型血吸虫病患者中，只有18.5%被发现患有PH。血吸虫病很少在没有明显肝脾表现的情况下导致PH。在此，我们报告一例患者，其首次临床表现为PH特征。我们以此病例为契机，概述PH的病理机制、病因和分类。强调对PH进行结构化和全面的检查。在没有阳性家族史和先进诊断技术的情况下，排除所有其他继发原因对于诊断原发性PH尤为重要。
