Hai Justine Hoda, Lee Cliff, Kapila Yvonne L, Chaffee Benjamin W, Armitage Gary C
Department to Orofacial Sciences, University of California San Francisco School of Dentistry, San Francisco, CA.
Department of Preventive and Restorative Sciences, University of California San Francisco, School of Dentistry, San Francisco, CA.
J Periodontol. 2020 Apr;91(4):508-515. doi: 10.1002/JPER.19-0195. Epub 2019 Aug 23.
The prevention of postoperative infection is often the basis for antibiotic prescription; however, the risks of unwarranted antibiotics and lack of guidelines for procedures involving bone grafts creates additional difficulty in decision making for practitioners. This study aims to evaluate practices in antibiotics prescribed for periodontal surgeries with and without bone grafting and acceptability of guidelines.
An anonymous survey was distributed to periodontists via the California Society of Periodontists e-mail listserv. The survey questioned prescribing practices for periodontal procedures, prescribing rationale, demographic and dental practice information, and acceptability of guidelines. Results were analyzed using McNemar tests and logistic regression.
Practitioners were significantly less likely to prescribe antibiotics for traditional periodontal surgeries without bone grafting compared with socket preservation, guided tissue regeneration, guided bone regeneration, and sinus augmentation (P < 0.0001). Practitioners were significantly more likely to prescribe antibiotics with more complex bone grafting such as guided bone regeneration and sinus augmentation compared with socket preservation (P < 0.0001). The most common rationale for prescribing antibiotics with bone grafting was to decrease the chances of developing an infection. Seventy-five percent of practitioners reported they would follow guidelines for antibiotic prescription if they were developed by the American Academy of Periodontology.
Practitioners are more likely to prescribe antibiotics with bone grafting and as complexity of the bone grafting procedure increases. Based on these results, the low incidence of infection in periodontal surgery cited in the literature, and willingness of practitioners to adopt guidelines, the establishment of evidence-based guidelines would be of benefit to the periodontal practicing community.
预防术后感染通常是抗生素处方的依据;然而,不必要使用抗生素的风险以及缺乏涉及骨移植手术的指南给从业者的决策带来了额外困难。本研究旨在评估在有或没有骨移植的牙周手术中抗生素的使用情况以及指南的可接受性。
通过加利福尼亚牙周病学会的电子邮件列表向牙周病医生发放了一份匿名调查问卷。该调查询问了牙周手术的处方习惯、处方理由、人口统计学和牙科执业信息以及指南的可接受性。使用 McNemar 检验和逻辑回归分析结果。
与牙槽窝保存、引导组织再生、引导骨再生和鼻窦增高术相比,从业者为不进行骨移植的传统牙周手术开抗生素的可能性显著降低(P < 0.0001)。与牙槽窝保存相比,从业者为更复杂的骨移植手术(如引导骨再生和鼻窦增高术)开抗生素的可能性显著增加(P < 0.0001)。进行骨移植时开抗生素最常见的理由是降低感染发生的几率。75%的从业者报告说,如果由美国牙周病学会制定抗生素处方指南,他们会遵循这些指南。
从业者在进行骨移植时更有可能开抗生素,并且随着骨移植手术复杂性的增加,开抗生素的可能性也增加。基于这些结果、文献中提到的牙周手术感染低发生率以及从业者采用指南的意愿,制定循证指南将对牙周临床界有益。