罗德岛医疗补助计划覆盖的孕妇中处方阿片类药物的使用情况
Prescription Opioid Use among Pregnant Women Enrolled in Rhode Island Medicaid.
作者信息
Wen Xuerong, Belviso Nicholas, Lebeau Rebecca, Bratberg Jeff, Cotton Brandi, Ward Kristina, Erickson-Owens Debra, Kogut Stephen
机构信息
Health Outcomes, Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island.
Executive Office of Human & Health Services, Rhode Island.
出版信息
R I Med J (2013). 2019 Aug 1;102(6):35-40.
OBJECTIVE
Our objective was to identify patterns of opioid use among pregnant women enrolled in RI Medicaid.
METHODS
This study used linked RI Medicaid and RI Birth Certificate data from 01/01/2006 to 12/31/2016. We examined temporal trends of prescription opioid dispensings and identified risk factors associated with opioids use during pregnancy.
RESULTS
Among 25,500 RI Medicaid enrolled pregnant women who delivered a live baby from 2008 to 2016, 1,914 (7.5%) received at least one prescription for an opioid medication during pregnancy, 810 (3.2%) were during the first trimester, 633 (2.5%) during the second trimester, and 866 (3.4%) during the third trimester. Of these, 213 (0.8%) women received 3 or more opioids during pregnancy. The prevalence of prescription opioids dispensed in pregnant women increased from 4.9% in 2008 to 9.6% in 2015 (β±SD: 0.66±0.28, P=0.05).
CONCLUSIONS
Prescription opioid use during pregnancy has increased among women enrolled in RI Medicaid.
目的
我们的目的是确定罗德岛医疗补助计划（RI Medicaid）登记在册的孕妇中阿片类药物的使用模式。
方法
本研究使用了2006年1月1日至2016年12月31日罗德岛医疗补助计划与罗德岛出生证明的关联数据。我们研究了处方阿片类药物配药的时间趋势，并确定了与孕期阿片类药物使用相关的风险因素。
结果
在2008年至2016年分娩活产婴儿的25,500名罗德岛医疗补助计划登记在册的孕妇中，1,914名（7.5%）在孕期至少接受过一次阿片类药物处方，其中810名（3.2%）在孕早期，633名（2.5%）在孕中期，866名（3.4%）在孕晚期。其中，213名（0.8%）女性在孕期接受了3种或更多阿片类药物。孕妇中处方阿片类药物的配药率从2008年的4.9%增至2015年的9.6%（β±标准差：0.66±0.28，P = 0.05）。
结论
罗德岛医疗补助计划登记在册的女性孕期处方阿片类药物的使用有所增加。
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