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脾脓肿作为肺外结核的罕见症状——病例报告

Splenic abscess as a rare symptom of the extrapulmonary tuberculosis - case report.

作者信息

Horák P, Horová B, Koutníková H, Marvan J, Fulík J, Fanta J

出版信息

Rozhl Chir. 2019 Summer;98(7):297-300.

Abstract

INTRODUCTION

Extrapulmonary tuberculosis can involve any organ or tissue. It is a rare disease in the Czech Republic with an incidence rate of 0.62 cases per 100.000 persons. It affects mostly immunocompromised patients. The most common sites include lymph nodes, the urogenital system, skin, joints, bones and serous epithelium - the peritoneum, pleura, and pericardium. Splenic involvement is rare. Mycobacterium is a slow growing intracellular parasite. The diagnostic process is very difficult; microbiological diagnosis is critical.

CASE REPORT

An 84 years old female patient with subcapsular splenic rupture with no trauma history as a cause of anemia. Splenic abscess was diagnosed during surgical revision and splenectomy. Tuberculosis was suspected based on subsequent histological analysis, which was confirmed after nine weeks of peritoneal fluid culture. The surgical procedure and postoperative hospitalization were not associated with any complications. The patient was referred to the respiratory clinic for further treatment.

CONCLUSION

The diagnosis of extrapulmonary tuberculosis including splenic localization should always be considered. A sample from the affected tissue or effusion must be collected in the case of unclear perioperative findings and sent for complete bacteriological testing, including mycobacterial culture. If a tuberculous splenic abscess is found, the therapeutic process should involve its complete drainage in combination with long-term anti-TB medication.

摘要

引言

肺外结核可累及任何器官或组织。在捷克共和国,这是一种罕见疾病,发病率为每10万人中有0.62例。它主要影响免疫功能低下的患者。最常见的部位包括淋巴结、泌尿生殖系统、皮肤、关节、骨骼和浆膜上皮——腹膜、胸膜和心包。脾脏受累较为罕见。分枝杆菌是一种生长缓慢的细胞内寄生虫。诊断过程非常困难;微生物学诊断至关重要。

病例报告

一名84岁女性患者,无外伤史,因贫血导致脾包膜下破裂。在手术探查和脾切除术中诊断出脾脓肿。根据随后的组织学分析怀疑为结核病,经腹膜液培养9周后得到证实。手术过程和术后住院均未出现任何并发症。患者被转诊至呼吸科门诊接受进一步治疗。

结论

应始终考虑包括脾脏定位在内的肺外结核的诊断。如果围手术期发现不明确,必须从受影响的组织或积液中采集样本,并送去进行包括分枝杆菌培养在内的完整细菌学检测。如果发现结核性脾脓肿,治疗过程应包括彻底引流并结合长期抗结核药物治疗。

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