Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, 1450 San Pablo St, HC4 - #5400A, Mail Code: 9224, Los Angeles, CA, 90033, USA.
Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Syst Rev. 2019 Aug 9;8(1):199. doi: 10.1186/s13643-019-1119-0.
Whiplash is a common traumatic cervical injury which is most often a consequence of rear-end motor vehicle accidents. It has been estimated that up to 50% of the whiplash patients suffer from chronic symptoms, resulting in extensive individual and societal burden. Several measurement instruments are used for initial assessment of whiplash and evaluation of response to treatment. However, a comprehensive assessment of the performance of these measures is lacking. Furthermore, there is no consensus on the most relevant outcome domains and their corresponding measurement instruments of choice. This systematic review aims to identify, describe, and critically appraise the performance properties of health-related measurement instruments in whiplash population.
The following literature databases will be searched from their date of establishment: PubMed, Embase®, MEDLINE, CINAHL Complete, PsycINFO, and HAPI. All original articles evaluating the reliability, validity, responsiveness, and feasibility of health-related measurement instruments in whiplash will be included, without additional restriction on their intended use, source of data, and structure. Risk of bias will be assessed using the COSMIN Risk of Bias checklist. Findings of the studies will be judged against the criteria for good measurement properties, and results from all studies will be qualitatively summarized to generate an overall quality of findings. Overall quality of evidence will be determined using a modified GRADE approach, which will be used in conjunction with the overall quality of results for generation of recommendations. Two reviewers will perform all steps of the review independently. Discrepancies will be discussed between the reviewers, and in case of remaining disagreement, the senior reviewer will make the final decision.
This systematic review will summarize the body of literature on health-related measurement instruments in whiplash, aiming to facilitate the selection of high-quality measurement instrument for researchers and physicians. Findings of this study will guide the ongoing efforts for development of a core outcome set.
PROSPERO reference number CRD42018070901.
挥鞭伤是一种常见的创伤性颈椎损伤，通常是汽车追尾事故的后果。据估计，多达 50%的挥鞭伤患者患有慢性症状，给个人和社会带来了巨大的负担。有几种测量工具用于初步评估挥鞭伤和评估治疗反应。然而，这些措施的性能综合评估却缺乏。此外，对于最相关的结果领域及其相应的首选测量工具，尚无共识。本系统评价旨在确定、描述和批判性地评估与健康相关的测量工具在挥鞭伤人群中的性能。
将从建立日期起搜索以下文献数据库：PubMed、Embase®、MEDLINE、CINAHL Complete、PsycINFO 和 HAPI。所有评估健康相关测量工具可靠性、有效性、反应性和可行性的原始文章，无论其预期用途、数据来源和结构如何，都将被包括在内。将使用 COSMIN 偏倚风险检查表评估偏倚风险。研究结果将根据良好测量特性的标准进行判断，所有研究的结果将进行定性总结，以产生总体发现质量。使用改良的 GRADE 方法确定证据的总体质量，该方法将与结果的总体质量结合使用，以生成建议。两名审查员将独立执行审查的所有步骤。审查员之间的差异将进行讨论，如果仍然存在分歧，资深审查员将做出最终决定。
本系统评价将总结挥鞭伤相关健康测量工具的文献，旨在为研究人员和医生选择高质量的测量工具提供便利。该研究的结果将指导正在进行的核心结局集开发工作。
PROSPERO 参考编号 CRD42018070901。
