Tsehay Binalfew, Shitie Desalegn, Lake Akilog, Abebaw Erimiyas, Taye Amisalu, Essa Enatinesh
Department of Biomedical Sciences, Debre Markos University, Debre Markos, Ethiopia.
Department of Gynecology and Obstetrics, Debre Markos Referral Hospital, Debre Markos, Ethiopia.
BMC Res Notes. 2019 Aug 9;12(1):495. doi: 10.1186/s13104-019-4541-4.
Although infant mortality because of birth defect has increased in both developed and developing countries, had not got attention like other health issues at national, regional, or local levels. Documenting the risk factors that influence the occurrence of birth defects and its seasonality will help to inform the community and to develop preventive strategies for the country.
Factors associated with higher likelihood of a major structural birth defects included maternal age; neonates born from women living in urban; and in Dega; history of fever during pregnancy; intake of herbal medicine; and drinking alcohol. Counselling for pregnancy preparation and folic acid supplementation was found protective for the likelihood of birth defect.
尽管发达国家和发展中国家因出生缺陷导致的婴儿死亡率均有所上升，但在国家、区域或地方层面，该问题并未像其他健康问题那样受到关注。记录影响出生缺陷发生的风险因素及其季节性，将有助于向社区提供信息，并为该国制定预防策略。
与主要结构性出生缺陷发生可能性较高相关的因素包括产妇年龄；城市地区及德加地区妇女所生新生儿；孕期发热史；服用草药；以及饮酒。发现孕前咨询和补充叶酸对降低出生缺陷的可能性具有保护作用。
