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Uncovering the mechanism of action of aspirin in HCC chemoprevention.

作者信息

Roehlen Natascha, Baumert Thomas F

机构信息

Inserm, U1110, Institute de Recherche sur les Maladies Virales et Hépatiques, 67000 Strasbourg, France; Université de Strasbourg, 67000 Strasbourg, France.

Inserm, U1110, Institute de Recherche sur les Maladies Virales et Hépatiques, 67000 Strasbourg, France; Université de Strasbourg, 67000 Strasbourg, France; IHU Strasbourg, Pole Hépato-digestif, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France.

出版信息

EBioMedicine. 2019 Aug;46:21-22. doi: 10.1016/j.ebiom.2019.07.047. Epub 2019 Aug 6.

Abstract
摘要

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本文引用的文献

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Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1.
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JAMA Oncol. 2018 Dec 1;4(12):1683-1690. doi: 10.1001/jamaoncol.2018.4154.
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Aspirin inhibits the proliferation of hepatoma cells through controlling GLUT1-mediated glucose metabolism.
Acta Pharmacol Sin. 2019 Jan;40(1):122-132. doi: 10.1038/s41401-018-0014-x. Epub 2018 Jun 20.
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By inhibiting PFKFB3, aspirin overcomes sorafenib resistance in hepatocellular carcinoma.
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Nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma.
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Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.
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