甲状腺伴嗜酸性粒细胞增多的硬化性黏液表皮样癌
Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid.
作者信息
Iftikhar Haissan, Awan Muhammad Sohail, Ghaloo Shayan Khalid, Fatima Saira
机构信息
Department of Surgery, Aga Khan University, Karachi, Pakistan.
Department of Pathology, Aga Khan University, Karachi, Pakistan.
出版信息
BMJ Case Rep. 2019 Aug 8;12(8):e225685. doi: 10.1136/bcr-2018-225685.
Sclerosing mucoepidermoid carcinoma of the thyroid was first reported in 1991. This tumour type may develop as associated to Hashimoto thyroiditis. There are two variants of mucoepidermoid carcinoma of thyroid. The conventional and the sclerosing variants. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid (SCME) has recently been recognised as a separate disease entity by the WHO. We report a case of SCME in a 62-year-old male patient who presented with a painless anterior neck swelling. Total thyroidectomy was performed, and no adjuvant treatment administered. The patient remained disease free up until 10 months of follow-up. Approximately 40 cases are reported in literature. We report the second case of SCME in Asian men. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid should be differentiated from the conventional mucoepidermoid carcinoma. Patients should also be advised of long-term follow-up for surveillance.
甲状腺硬化性黏液表皮样癌于1991年首次被报道。这种肿瘤类型可能与桥本甲状腺炎相关。甲状腺黏液表皮样癌有两种变体，即传统型和硬化型。甲状腺嗜酸细胞硬化性黏液表皮样癌（SCME）最近被世界卫生组织确认为一种独立的疾病实体。我们报告一例62岁男性患者的SCME，该患者表现为无痛性颈部前方肿胀。行全甲状腺切除术，未给予辅助治疗。在随访的10个月中，患者无疾病复发。文献报道约40例。我们报告亚洲男性中第二例SCME。甲状腺嗜酸细胞硬化性黏液表皮样癌应与传统黏液表皮样癌相鉴别。还应建议患者进行长期随访监测。
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