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肥胖与牙周炎相关性的研究进展:一种流行病学观点。

Review of obesity and periodontitis: an epidemiological view.

机构信息

Unit of Clinical Oral Epidemiology (UNIECLO) Investigations, School of Dentistry, El Bosque University, Bogotá, Colombia.

Department of Oral and Maxillofacial Medicine and Diagnostic Sciences, Case Western Reserve University, School of Dental Medicine and University Hospitals Cleveland Medical Centre, Cleveland, Ohio, USA.

出版信息

Br Dent J. 2019 Aug;227(3):235-239. doi: 10.1038/s41415-019-0611-1.

Abstract

Obesity and periodontitis are among the most common non-communicable diseases, and epidemiological studies report the influence of obesity in the onset and progression of periodontitis. Data indicate that increased body mass index, waist circumference, percentage of subcutaneous body fat, and serum lipid levels are associated with increased risk to develop periodontitis. The underlying biological mechanisms of this association involve adipose tissue-derived cytokines, such as tumour necrosis factor-α and interleukin-6, which affect whole-body metabolism and contribute to the development of a low-grade systemic inflammation. Multiple studies report a positive association between these two diseases across diverse populations. Obesity does not appear to impair the success of periodontal therapy. However, currently available evidence is variable and therefore inconclusive. Despite the limited evidence about recommendations on treatment planning, oral healthcare professionals need to be aware of the complexity of obesity to counsel their patients about the importance of maintaining healthy body weight and performing good oral hygiene procedures.

摘要

肥胖症和牙周炎是最常见的非传染性疾病之一,流行病学研究报告称肥胖症会影响牙周炎的发生和发展。数据表明,体重指数、腰围、体脂百分比和血清脂质水平的增加与牙周炎发病风险的增加有关。这种关联的潜在生物学机制涉及脂肪组织衍生的细胞因子,如肿瘤坏死因子-α和白细胞介素-6,它们影响全身代谢并有助于低度全身炎症的发展。多项研究报告称,这两种疾病在不同人群中存在正相关关系。肥胖症似乎不会影响牙周治疗的成功率。然而,目前的证据是可变的,因此结论并不确定。尽管关于治疗计划的建议证据有限,但口腔保健专业人员需要意识到肥胖症的复杂性,以便就保持健康体重和进行良好的口腔卫生程序的重要性为患者提供建议。

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