Centre for Rural Health, University of Tasmania, Hobart, Tas., Australia.
Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia.
Obes Rev. 2018 Jun;19(6):852-883. doi: 10.1111/obr.12668. Epub 2018 Jan 19.
Obesity in young adults and adolescents is associated with chronic co-morbidities. This project investigated whether being overweight or obese is a risk factor for periodontitis in adolescents (13-17 years) and young adults (18-34 years).
A search of 12 databases was conducted using Medical Subject Headings/Index and Emtree terms. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, articles published between 2003 and 2016 were screened that reported periodontal and anthropometric measures. The Newcastle-Ottawa Scale was used to appraise the quality of studies.
Of 25 eligible studies from 12 countries, 17 showed an association between obesity and periodontitis (odds ratios ranged from 1.1 to 4.5). The obesity indicators of body mass index, waist circumference, waist-hip ratio and body fat percentage were significantly associated with measures of periodontitis of bleeding on probing, plaque index, probing depths, clinical attachment loss, calculus, oral hygiene index and community periodontal index. Two prospective cohort studies in the review showed no significant association between obesity and periodontitis, but these studies had limitations of study design and used inappropriate epidemiological diagnostic measures of periodontitis.
There was evidence to suggest that obesity is associated with periodontitis in adolescents and young adults. Systematic Review Registration: PROSPERO Registration Number: CRD42016046507.
年轻人和青少年的肥胖与慢性合并症有关。本项目研究了超重或肥胖是否是青少年（13-17 岁）和年轻人（18-34 岁）牙周炎的危险因素。
使用 Medical Subject Headings/Index 和 Emtree 术语对 12 个数据库进行了搜索。根据系统评价和荟萃分析的首选报告项目，筛选了 2003 年至 2016 年期间发表的报告牙周和人体测量指标的文章。纽卡斯尔-渥太华量表用于评估研究质量。
从 12 个国家的 25 项合格研究中，有 17 项研究表明肥胖与牙周炎之间存在关联（比值比范围为 1.1 至 4.5）。体重指数、腰围、腰臀比和体脂百分比等肥胖指标与探诊出血、菌斑指数、探诊深度、临床附着丧失、牙石、口腔卫生指数和社区牙周指数等牙周炎指标显著相关。综述中的两项前瞻性队列研究表明肥胖与牙周炎之间没有显著关联，但这些研究存在研究设计的局限性，并使用了不适当的牙周炎流行病学诊断措施。
有证据表明肥胖与青少年和年轻人的牙周炎有关。系统评价注册：PROSPERO 注册编号：CRD42016046507。
