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利用全极电图将生理学重新引入心脏标测

Reinserting Physiology into Cardiac Mapping Using Omnipolar Electrograms.

作者信息

Magtibay Karl, Porta-Sánchez Andreu, Haldar Shouvik K, Deno Don Curtis, Massé Stéphane, Nanthakumar Kumaraswamy

机构信息

The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada.

Hospital Universitario Quironsalud Madrid, Calle Diego de Velázquez, 1, 28223 Pozuelo de Alarcón, Madrid, Spain; Fundacion Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro, 3, Madrid 28029, Spain.

出版信息

Card Electrophysiol Clin. 2019 Sep;11(3):525-536. doi: 10.1016/j.ccep.2019.05.003.

Abstract

Omnipolar electrograms (EGMs) make use of biophysical electric fields that accompany activation along the surface of the myocardium. A grid-like electrode array provides bipolar signals in orthogonal directions to deliver catheter-orientation-independent assessments of cardiac electrophysiology. Studies with myocyte monolayers, isolated animal and human hearts, and anesthetized animals validated the tenets of omnipolar EGMs. The combination of information from omnipolar-based activation vectors and voltages may aid in localizing areas of scar, lesion gaps, wavefront disorganization, and fractionation or collision during arrhythmias. The goal of omnipolar EGMs is to better characterize myocardium through reintroducing electrogram direction related fundamentals of cardiac electrophysiology.

摘要

全极电图(EGMs)利用心肌表面激活时伴随的生物物理电场。一种网格状电极阵列在正交方向上提供双极信号,以进行与导管方向无关的心脏电生理评估。对心肌细胞单层、离体动物和人类心脏以及麻醉动物的研究验证了全极电图的原理。基于全极的激活向量和电压信息的结合可能有助于定位疤痕区域、病变间隙、波前紊乱以及心律失常期间的碎裂或碰撞区域。全极电图的目标是通过重新引入与心电图方向相关的心脏电生理基本原理来更好地表征心肌。

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