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1985年欧洲儿童透析与移植人口统计学。欧洲透析与移植协会登记处报告。

Demography of dialysis and transplantation in children in Europe, 1985. Report from the European Dialysis and Transplant Association Registry.

出版信息

Nephrol Dial Transplant. 1988;3(3):235-43.

PMID:3140094
Abstract

At the end of 1985 there were 5482 patients known to the Registry who started renal replacement therapy (RRT) between the ages of 6 months and 15 years. Of these, approximately 25% had died, 30% were still aged less than 15 years, and the other 45% were older. The acceptance rate of new patients over the last 10 years has slowly but steadily increased; six new paediatric patients per million child population probably represents the likely needs of the near future. Hospital haemodialysis remained the main form of renal replacement therapy in new patients, while 3 years after start of RRT, transplantation became the most frequently used replacement therapy; CAPD appeared to be used mainly in children with a short waiting time for transplantation. Out of the 384 grafts reported in 1985, only 16% were from living related donors; among 321 cadaver grafts, 24% were second and only 3% were third grafts. Glomerulonephritis and pyelonephritis accounted for 50% of all primary renal diseases. During the last 5 years, the proportion with glomerulonephritis seems to have decreased slightly. Hyperkalaemia and fluid overload have still to be considered the main causes of death. Only in 17% of all cases was the cause of death reported as unknown or undetermined.

摘要

1985年底,登记处记录了5482名年龄在6个月至15岁之间开始接受肾脏替代治疗(RRT)的患者。其中,约25%已死亡,30%年龄仍小于15岁,另外45%年龄较大。过去10年新患者的接受率缓慢但稳步上升;每百万儿童人口中有6名新的儿科患者可能代表了近期的可能需求。医院血液透析仍是新患者肾脏替代治疗的主要形式,而在开始RRT 3年后,移植成为最常用的替代治疗方法;持续性非卧床腹膜透析(CAPD)似乎主要用于等待移植时间较短的儿童。在1985年报告的384例移植中,只有16%来自活体亲属供体;在321例尸体供体移植中,24%是第二次移植,只有3%是第三次移植。肾小球肾炎和肾盂肾炎占所有原发性肾脏疾病的50%。在过去5年中,肾小球肾炎患者的比例似乎略有下降。高钾血症和液体超负荷仍是主要死因。所有病例中只有17%的死亡原因报告为未知或未确定。

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