保加利亚广泛存在托斯卡纳病毒感染的血清学证据。
Serologic evidence of widespread Toscana virus infection in Bulgaria.
机构信息
National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.
National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.
出版信息
J Infect Public Health. 2020 Feb;13(2):164-166. doi: 10.1016/j.jiph.2019.07.008. Epub 2019 Aug 7.
BACKGROUND
Toscana virus (TOSV) is an emerging sandfly-borne virus that is endemic in Mediterranean countries.
METHODS
In order to detect TOSV circulation among the human population of Bulgaria, serum samples from 459 apparently healthy adult individuals, residing in19 out of 28 districts in the country, were tested for the presence of IgG antibodies to TOSV.
RESULTS
An overall seroprevalence rate of 24.4% was observed, ranging from 4.4% to 53.5% in the districts. Rates were highest in persons over 60 years of age and residing in the southern districts.
CONCLUSION
The results of the first TOSV seroprevalence study in Bulgaria revealed that infection is widespread. Physicians should be aware of the virus circulation during summer and consider the diagnosis in cases of febrile illness, meningitis or meningoencephalitis.
背景
托斯卡纳病毒（TOSV）是一种新兴的沙蝇传播病毒，在地中海国家流行。
方法
为了检测保加利亚人群中 TOSV 的传播情况，对来自该国 28 个区中的 19 个区的 459 名明显健康的成年人的血清样本进行了 TOSV IgG 抗体检测。
结果
观察到总体血清阳性率为 24.4%，各区的范围为 4.4%至 53.5%。年龄在 60 岁以上和居住在南部地区的人群中阳性率最高。
结论
保加利亚首例 TOSV 血清流行率研究的结果表明，该病毒的感染非常普遍。医生在夏季应注意病毒的传播，并在出现发热性疾病、脑膜炎或脑膜脑炎时考虑诊断。
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