肾移植后硫唑嘌呤治疗与肝脏结节性再生性增生有关吗？
Is nodular regenerative hyperplasia of the liver associated with azathioprine therapy after renal transplantation?
作者信息
Jones M C, Best P V, Catto G R
机构信息
Department of Medicine, University of Aberdeen, Aberdeen Royal Infirmary, Foresterhill, UK.
出版信息
Nephrol Dial Transplant. 1988;3(3):331-3.
PMID:3140109
Abstract
A 33-year-old man presented with hepatosplenomegaly and ascites 26 months after receiving a successful renal transplant. Immunosuppression consisted of low-dose prednisolone and azathioprine. Biopsy showed characteristic features of nodular regenerative hyperplasia of liver (NRHL), a condition which may be related to azathioprine therapy but has rarely been reported in association with renal transplantation.
摘要
一名33岁男性在肾移植成功26个月后出现肝脾肿大和腹水。免疫抑制治疗包括小剂量泼尼松龙和硫唑嘌呤。活检显示为肝脏结节性再生性增生（NRHL）的特征性表现，这种情况可能与硫唑嘌呤治疗有关，但与肾移植相关的报道很少。
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