Department of Biomedical Sciences for Health, University of Milan , Milan , Italy.
IRCCS Istituto Ortopedico Galeazzi , Milan , Italy.
Chronobiol Int. 2019 Oct;36(10):1311-1315. doi: 10.1080/07420528.2019.1650059. Epub 2019 Aug 12.
We have recently shown that rest-activity circadian rhythm significantly differed in women with Binge Eating Disorder (BED) compared to the Ctrl group. In details, patients with BED exhibited significantly reduced levels of MESOR and Amplitude with respect to the Ctrl group. In addition, in this previous study, the results of the actigraphic sleep monitoring provided no evidence of differences in sleep parameters between the two groups. We expanded the original sample obtaining a total of 28 volunteered women, 14 BED women, and 14 Ctrl. We recorded in all 28 participants a 5-day actigraphic monitoring to detect the rhythmometric parameters, interdaily stability, intradaily variability, L5, M10, and sleep parameters. During the study, BED's women group kept an individual multidisciplinary therapy lasting five weekly days, from Monday to Friday, consisting in cognitive-behavioral therapy and nutritional program, administered in outpatient care from 8:00 a.m. at 5:00 p.m. The combination of both our previous and current study supports the conclusion that the sleep quality of the BED group is significantly better compared to Ctrl. The non-parametric indexes showed how interdaily stability, significantly correlated to sleep efficiency, was higher in BED group compared to the Ctrl group, indicating a better synchronization of rest-activity circadian rhythm. In conclusion, the maintenance of a regular lifestyle, such as imposed by the multidisciplinary therapy, is important to avoid alterations in the sleep-wake cycle, particularly in patients with eating disorders.
我们最近发现,与对照组相比,暴食症患者的静息-活动昼夜节律有明显差异。具体来说,与对照组相比,暴食症患者的 MESOR 和振幅显著降低。此外,在这项之前的研究中,活动记录仪睡眠监测的结果没有显示两组之间睡眠参数存在差异。我们扩展了原始样本,共招募了 28 名志愿者,其中 14 名为暴食症患者,14 名为对照组。我们对所有 28 名参与者进行了为期 5 天的活动记录仪监测,以检测节律参数、日间稳定性、日内变异性、L5、M10 和睡眠参数。在研究过程中,暴食症患者组进行了为期 5 天的个体化多学科治疗,从周一到周五,包括认知行为疗法和营养计划,在门诊治疗中从上午 8 点到下午 5 点进行。我们之前和现在的研究结果都支持这样的结论,即与对照组相比,暴食症患者的睡眠质量显著更好。非参数指标显示,日间稳定性与睡眠效率显著相关,在暴食症组中明显高于对照组,表明静息-活动昼夜节律的同步性更好。总之,保持有规律的生活方式,如多学科治疗所要求的那样,对于避免睡眠-觉醒周期的改变很重要,特别是对于饮食障碍患者。