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沙特阿拉伯吉达学术中心足月儿呼吸窘迫综合征的发病率、危险因素及转归

Incidence, Risk factors and Outcome of Respiratory Distress Syndrome in Term Infants at Academic Centre, Jeddah, Saudi Arabia.

作者信息

Alfarwati Tariq W, Alamri Abdullah A, Alshahrani Mubarak A, Al-Wassia Heidi

机构信息

Neonatal Intensive Care Unit, College of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Department of Pediatrics, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

出版信息

Med Arch. 2019 Jun;73(3):183-186. doi: 10.5455/medarh.2019.73.183-186.

Abstract

INTRODUCTION

Respiratory distress syndrome (RDS) is a respiratory disorder of neonates that manifests itself within few hours after delivery. It is one of the most common causes of admission to neonatal intensive care unit (NICU) and respiratory failure in neonates.

AIM

The aim of this study was to determine the incidence, risk factors, and the short-term outcomes of RDS in term infants born in an academic tertiary care center at King Abdul-Aziz University Hospital (KAUH), Jeddah, Saudi Arabia.

METHODS

Data of all infants admitted to the NICU at the academic center between January 1 2016 and December 31 2016 were retrospectively collected. Cases were all term infants who were admitted to NICU with the diagnosis of RDS during the study period. Controls were term infants and 1:1 matched for the date of birth (one or two days from the date of birth of the case) and received routine newborn care.

RESULTS

Fifty-nine term infants (59/3601, 1.64%) were admitted to the NICU with RDS and 59 control infants were matched during the study period. Infants with RDS were significantly of lower birth weight and had lower Apgar scores at one and five minutes. Although there was a higher number of cesarean section and PROM in the RDS group, but that didn't reach statistical significance. Three infants (5.1%) died in the RDS group.

CONCLUSION

Respiratory distress in term infants is still a significant cause of admission to NICU and a predisposing factor for neonatal mortality and morbidity. Preventative and anticipatory measures should be further explored to decrease the burden of this disease.

摘要

引言

呼吸窘迫综合征(RDS)是一种新生儿呼吸系统疾病,在出生后数小时内出现。它是新生儿重症监护病房(NICU)收治和新生儿呼吸衰竭的最常见原因之一。

目的

本研究旨在确定沙特阿拉伯吉达阿卜杜勒-阿齐兹国王大学医院(KAUH)一所学术性三级医疗中心足月出生婴儿中RDS的发病率、危险因素和短期结局。

方法

回顾性收集2016年1月1日至2016年12月31日期间该学术中心NICU收治的所有婴儿的数据。病例为研究期间因RDS诊断入住NICU的所有足月婴儿。对照组为足月婴儿,按出生日期(病例出生日期的一天或两天内)1:1匹配,并接受常规新生儿护理。

结果

59名足月婴儿(59/3601,1.64%)因RDS入住NICU,研究期间匹配了59名对照婴儿。RDS婴儿出生体重显著较低,1分钟和5分钟时阿氏评分较低。虽然RDS组剖宫产和胎膜早破的数量较多,但未达到统计学意义。RDS组有3名婴儿(5.1%)死亡。

结论

足月婴儿呼吸窘迫仍然是入住NICU的重要原因,也是新生儿死亡和发病的一个诱发因素。应进一步探索预防和预期措施,以减轻这种疾病的负担。

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