van Coppenhagen Brett, Duvenage Helene S
Department of Family Medicine, University of Pretoria, Pretoria, South Africa.
S Afr J Psychiatr. 2019 Jul 22;25:1175. doi: 10.4102/sajpsychiatry.v25i0.1175. eCollection 2019.
Compared to the general population, there is an increased prevalence of depression in people living with HIV and AIDS (PLWHA). The combination of these two common illnesses has profound consequences on the patient and on the healthcare system.
This study determined the prevalence of depressive symptomatology in PLWHA attending the Kalafong Hospital ARV Clinic. The study also established if the patients received definitive treatment for unipolar depression.
A cross-sectional, descriptive study was carried out on 622 adult patients, aged 18 years or older. A brief rating scale for depression, the Centre for Epidemiological Study Depression Scale (CES-D) was administered to participants. The CES-D is a 20-item self-rating scale that assesses current levels of depression as per DSM-IV criteria. The traditional score of 16 and above was used to define a case of depression.
The prevalence of depression according to CES-D scale was 53.8%. The study found that none of the 622 patients ever received definitive treatment for depression. A lower CD4 count is associated with more depressive symptomatology, most significantly in patients with a CD4 count of 50 or less.
Depressive symptomatology was highly prevalent in the study patients. Despite the high prevalence, none of the study sample patients were treated for clinical depression. The findings reflect the importance of evaluating for depression in PLWHA, especially in high-risk groups such as patients presenting for their initiation visit or patients with a CD4 count of 50 or less. Depression remains under-recognised and under-treated in PLWHA.
与普通人群相比,感染艾滋病毒和患艾滋病的人(PLWHA)中抑郁症的患病率有所增加。这两种常见疾病的结合对患者和医疗系统都产生了深远影响。
本研究确定了在卡拉方医院抗逆转录病毒诊所就诊的PLWHA中抑郁症状的患病率。该研究还确定了患者是否接受了单相抑郁症的明确治疗。
对622名18岁及以上的成年患者进行了一项横断面描述性研究。向参与者发放了一份简短的抑郁评定量表,即流行病学研究中心抑郁量表(CES-D)。CES-D是一个包含20个条目的自评量表,根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准评估当前的抑郁水平。传统上,16分及以上被用来定义一例抑郁症。
根据CES-D量表,抑郁症的患病率为53.8%。研究发现,622名患者中没有一人曾接受过抑郁症的明确治疗。较低的CD4细胞计数与更多的抑郁症状相关,在CD4细胞计数为50或更低的患者中最为显著。
抑郁症状在研究患者中非常普遍。尽管患病率很高,但研究样本中的患者均未接受临床抑郁症治疗。这些发现反映了在PLWHA中评估抑郁症的重要性,特别是在高危人群中,如初次就诊的患者或CD4细胞计数为50或更低的患者。PLWHA中的抑郁症仍然未得到充分认识和治疗。