Almallouhi Eyad, Rahwan Mohamad, Dainton Helen, Bonilha Leonardo
Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA.
Avicenna J Med. 2019 Jul-Sep;9(3):119-121. doi: 10.4103/ajm.AJM_7_19.
Serotonin syndrome is a life-threatening condition. Seizure is one of the complications of serotonin syndrome that may delay diagnosis and complicate management. We report a patient who had a focal seizure with abnormal electroencephalogram in the setting of serotonin syndrome with no prior history of epilepsy or seizure-provoking factors (fever, electrolyte abnormalities, specific medication combinations, and specific medication overdosing). Recognition of seizure as a symptom of serotonin syndrome is important for early treatment and avoidance of long-term consequences. Treatment of serotonin syndrome is mostly supportive. However, a short course of antiepileptics may be needed if these patients develop seizures.
血清素综合征是一种危及生命的病症。癫痫发作是血清素综合征的并发症之一，可能会延迟诊断并使治疗复杂化。我们报告了一名患者，该患者在血清素综合征背景下出现局灶性癫痫发作，脑电图异常，既往无癫痫病史或癫痫诱发因素（发热、电解质异常、特定药物组合及特定药物过量）。认识到癫痫发作是血清素综合征的一种症状对于早期治疗及避免长期后果很重要。血清素综合征的治疗大多是支持性的。然而，如果这些患者出现癫痫发作，可能需要短期使用抗癫痫药物。
