Department of Urology, University of Washington, Seattle, WA.
Department of Urology, University of Washington, Seattle, WA.
Urology. 2019 Nov;133:50-56. doi: 10.1016/j.urology.2019.07.030. Epub 2019 Aug 9.
To describe trends in computed tomography (CT) use and estimate the radiation exposure among stone formers using a national insurance claims database.
Within MarketScan, adult stone patients from 2007 to 2013 were identified using International Classification of Diseases-Revision 9, International Classification of Diseases-Revision 10, and Current Procedural Terminology codes. Patients were classified as "active" (≥2 diagnosis codes for nephrolithiasis, or receipt of stone surgery) or "inactive" (1 stone diagnosis) and compared to age- and gender-matched controls. CT utilization was tracked over 3 years for each group. Annual CT-related radiation exposure was estimated using previously published dose values and compared using Kruskal-Wallis and χ tests. Demographic factors associated with greater CT exposure were identified on multivariate logistic regression.
Of active stone patients, 112,140 underwent surgery and 215,376 were managed nonoperatively. There were 175,228 inactive stone patients and 502,744 controls. On average, active stone patients received nearly 10 times as many CTs as controls at 3 years (P <.001), and more acute imaging (P <.001). About 25% and 15% of operative and nonoperative patients, respectively, received ≥3 CTs in 3 years. This was associated with female gender. For nonoperative patients, this was also associated with age, residence in the North-Central or South regions, and inversely associated with metropolitan residence (all P <.01). Over 10% of active stone patients are estimated to receive >20 mSv in the first year alone.
CT use and nonsurgical radiation exposure for active stone patients is significant. Over 10% are estimated to exceed occupational limits in the first year. Judicious CT imaging and low-dose protocols are critical for stone patients.
利用国家保险索赔数据库描述 CT 检查的使用趋势,并估算结石患者的辐射暴露量。
在 MarketScan 中,通过使用国际疾病分类第 9 版、第 10 版和当前操作术语代码,确定 2007 年至 2013 年期间的成年结石患者。患者分为“活跃”(至少 2 个肾结石诊断代码或接受结石手术)或“非活跃”(1 个结石诊断),并与年龄和性别匹配的对照者进行比较。对每组患者进行 3 年的 CT 利用情况跟踪。使用先前发表的剂量值估算每年与 CT 相关的辐射暴露量,并使用 Kruskal-Wallis 和 χ2 检验进行比较。使用多变量逻辑回归确定与更高 CT 暴露相关的人口统计学因素。
活跃的结石患者中,有 112140 例接受了手术,215376 例非手术治疗。有 175228 例非活跃结石患者和 502744 例对照者。平均而言,活跃的结石患者在 3 年内接受的 CT 检查次数是对照者的近 10 倍(P<.001),并且进行了更多的急性影像学检查(P<.001)。分别约有 25%和 15%的手术和非手术患者在 3 年内接受了≥3 次 CT 检查。这与女性性别有关。对于非手术患者,这也与年龄、居住在中北部或南部地区以及与大都市居住相反有关(均 P<.01)。估计超过 10%的活跃结石患者仅在第一年就接受了超过 20 mSv 的辐射。
活跃结石患者的 CT 检查使用和非手术辐射暴露量很大。估计超过 10%的患者在第一年就超过了职业限制。明智地进行 CT 成像和使用低剂量方案对结石患者至关重要。