纤毛在发育中。

Living Systems Institute, Biosciences, College of Life and Environmental Science, University of Exeter, Exeter, EX4 4QD, UK.

Curr Opin Genet Dev. 2019 Aug;57:25-30. doi: 10.1016/j.gde.2019.06.005. Epub 2019 Aug 9.

Cell-cell communication is essential during the development of multicellular organisms. Specialized cell protrusions called cytonemes have been identified to exchange signals between cells that are vital for tissue development. Cytonemes can carry signalling components between distant cells and thus regulate the activity levels of the corresponding signalling pathways across entire tissues. This review summarizes the key findings on the formation and function of cytonemes in tissue development.

细胞间通讯在多细胞生物的发育过程中至关重要。已经鉴定出专门的细胞突起，称为纤毛，用于在对组织发育至关重要的细胞之间交换信号。纤毛可以在远距离细胞之间传递信号成分，从而调节整个组织中相应信号通路的活性水平。本综述总结了关于纤毛在组织发育中的形成和功能的关键发现。