Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Sci Rep. 2019 Aug 12;9(1):11588. doi: 10.1038/s41598-019-48112-5.
This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were -5.3 ± 4.2%, -4.4 ± 4.4%, and -3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
本研究旨在探讨黄斑裂孔视网膜脱离（RD）术后复视严重程度的变化，以及复视与视网膜微观结构之间的关系。该研究纳入了 26 例（26 只眼）接受 RD 手术的患者。术前、术后 3、6 和 12 个月测量视力，术后 3、6 和 12 个月测量等效球镜值和 OCT 图像。术后 3、6 和 12 个月的等效球镜值（平均值±标准差）分别为-5.3±4.2%、-4.4±4.4%和-3.1±3.2%。术后 12 个月时，等效球镜值显著改善（P=0.001）。术后 12 个月时，14 只眼出现小视，1 只眼出现大视，11 只眼无复视。逐步多元回归分析显示，术后 12 个月的复视严重程度与术后囊样黄斑水肿（CME）和视网膜前膜（ERM）的发展以及术前 RD 面积显著相关。总之，尽管在 1 年的随访期间，RD 手术后复视逐渐缓解，但仍有约一半的患者存在复视，且几乎所有患者均有小视。复视与术后 CME、ERM 和术前 RD 面积有关。
