Senthilkumaran Subramanian, Benita Florence, Nath Jena Narendra, Sasikumar Sambathkumar, Thirumalaikolundusubramanian Ponniah
Department of Emergency and Critical Care, Manian Medical Center, Erode, Tamil Nadu, India.
Department of Emergency Medicine, DM Wayanad Institute of Medical Sciences, Wayanad, Kerala, India.
Indian J Crit Care Med. 2019 Jul;23(7):342-343. doi: 10.5005/jp-journals-10071-23211.
A case of high anion gap metabolic acidosis (HAGMA) and high level of 5-oxoprolinuria were noticed in an elderly female of 66 years who had multiple risk/precipitating factors and recovered well with N-acetyl cysteine infusion. This is reported in view of its rarity and to create awareness of this entity among medical students and practicing physicians who handles such cases in emergency room or critical care unit. Moreover they have to remember and investigate the cases of metabolic acidosis for 5-oxoprolinuia especially in susceptible individuals who are on paracetamol with or without other precipitating factors.
Senthilkumaran S, Benita F, Jena NN, Sasikumar S, Thirumalaikolundusubramanian P. 5-oxoprolinuria (Pyroglutamic Aciduria) and Metabolic Acidosis: Unraveling the Mystery. Indian J Crit Care Med 2019;23(7):342-343.
在一名66岁的老年女性中发现了一例高阴离子间隙代谢性酸中毒（HAGMA）和高水平的5-氧脯氨酸尿症，该患者有多种风险/诱发因素，经N-乙酰半胱氨酸输注后恢复良好。鉴于其罕见性，现将此病例报告出来，以提高医学生和在急诊室或重症监护病房处理此类病例的执业医师对该疾病的认识。此外，他们必须记住并调查代谢性酸中毒患者是否存在5-氧脯氨酸尿症，特别是对于正在服用对乙酰氨基酚且有或无其他诱发因素的易感个体。
Senthilkumaran S, Benita F, Jena NN, Sasikumar S, Thirumalaikolundusubramanian P. 5-氧脯氨酸尿症（焦谷氨酸尿症）与代谢性酸中毒：揭开谜团。《印度重症监护医学杂志》2019年；23(7):342 - 343。
