Lei Mengjie, Liu Tingting, Li Yufeng, Liu Yaqian, Meng Lina, Jin Changde
Department of Nursing, School of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Int J Nurs Sci. 2018 Jan 31;5(1):89-97. doi: 10.1016/j.ijnss.2018.01.004. eCollection 2018 Jan 10.
This meta-analysis aims to systematically evaluate the effects of massage on infants with jaundice.
Multiple electronic databases, including Cochrane Library, PubMed, EMBASE, Web of Science, China Biology Medicine (CBM), Wan Fang Data, VIP Database for Chinese Technical Periodicals and China National Knowledge Infrastructure (CNKI), were used to search for studies on the effects of massage on infants with jaundice. Data were analysed by Rev Man 5.3.
A total of 14 randomised controlled trials with 1889 patients were included. Statistically significant difference in percutaneous bilirubin [ = -1.21, 95% CI (-1.90, -0.52), < 0.05; = -2.00, 95% CI (-2.68, -1.32), < 0.05; = -2.00, 95% CI (2.56, -1.44), < 0.05; = -1.93, 95% CI (-2.44, -1.43), < 0.05] was found between two groups at 48, 72, 96 and 168 h. Studies on the serum total bilirubin level were divided into two subgroups according to sample size, and the results of subgroup analysis showed that the serum total bilirubin level in the intervention group was significantly lower than that in the control group [ = -52.06, 95% CI (-57.76, -46.36), < 0.05 and = -10.65, 95% CI (-14.66, -6.63), < 0.05]. Statistically significant difference in defecation frequency was observed between the two groups at 48 h after birth[ = 0.44, 95%CI (0.02, 0.87), < 0.05].
Massage can decrease serum total bilirubin and percutaneous bilirubin levels and increasing defecation frequency. However, due to heterogeneity among studies, numerous multi-centre, large-sample and high-quality randomised controlled trials are needed to verify the effects of massage.
本荟萃分析旨在系统评价按摩对黄疸婴儿的影响。
使用多个电子数据库，包括考克兰图书馆、PubMed、EMBASE、科学网、中国生物医学文献数据库（CBM）、万方数据、中文科技期刊数据库（维普）和中国知网（CNKI），检索关于按摩对黄疸婴儿影响的研究。采用Rev Man 5.3软件进行数据分析。
共纳入14项随机对照试验，涉及1889例患者。在出生后48、72、96和168小时时，两组间经皮胆红素水平存在统计学显著差异[I²=-1.21，95%置信区间（-1.90，-0.52），P<0.05；I²=-2.00，95%置信区间（-2.68，-1.32），P<0.05；I²=-2.00，95%置信区间（2.56，-1.44），P<0.05；I²=-1.93，95%置信区间（-2.44，-1.43），P<0.05]。根据样本量对血清总胆红素水平的研究进行亚组分析，结果显示干预组血清总胆红素水平显著低于对照组[I²=-52.06，95%置信区间（-57.76，-46.36），P<0.05和I²=-10.65，95%置信区间（-14.66，-6.63），P<0.05]。出生后48小时时，两组间排便频率存在统计学显著差异[I²=0.44，95%置信区间（0.02，0.87），P<0.05]。
按摩可降低血清总胆红素和经皮胆红素水平，并增加排便频率。然而，由于各研究间存在异质性，需要开展大量多中心、大样本和高质量的随机对照试验来验证按摩的效果。
