Robinson P J, Sly P D, Smith A L
Department of Thoracic Medicine, Royal Children's Hospital, Melbourne, Australia.
Arch Dis Child. 1988 Sep;63(9):1081-2. doi: 10.1136/adc.63.9.1081.
Misoprostol, a synthetic prostaglandin that is known to reduce gastric acid production and stimulate duodenal bicarbonate production, was evaluated in 22 patients with cystic fibrosis. In those patients who had greater than 10% fat malabsorption while taking pancrease the addition of misoprostol significantly reduced the degree of fat malabsorption.
米索前列醇是一种合成前列腺素,已知它能减少胃酸分泌并刺激十二指肠碳酸氢盐的分泌。对22例囊性纤维化患者进行了米索前列醇的评估。在那些服用胰酶时脂肪吸收不良超过10%的患者中,加用米索前列醇显著降低了脂肪吸收不良的程度。