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米索前列醇对囊性纤维化脂肪吸收不良的影响。

Effect of misoprostol on fat malabsorption in cystic fibrosis.

作者信息

Robinson P J, Sly P D, Smith A L

机构信息

Department of Thoracic Medicine, Royal Children's Hospital, Melbourne, Australia.

出版信息

Arch Dis Child. 1988 Sep;63(9):1081-2. doi: 10.1136/adc.63.9.1081.

Abstract

Misoprostol, a synthetic prostaglandin that is known to reduce gastric acid production and stimulate duodenal bicarbonate production, was evaluated in 22 patients with cystic fibrosis. In those patients who had greater than 10% fat malabsorption while taking pancrease the addition of misoprostol significantly reduced the degree of fat malabsorption.

摘要

米索前列醇是一种合成前列腺素,已知它能减少胃酸分泌并刺激十二指肠碳酸氢盐的分泌。对22例囊性纤维化患者进行了米索前列醇的评估。在那些服用胰酶时脂肪吸收不良超过10%的患者中,加用米索前列醇显著降低了脂肪吸收不良的程度。

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Placebo-controlled trial of misoprostol in cystic fibrosis.米索前列醇治疗囊性纤维化的安慰剂对照试验。
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本文引用的文献

1
Gastric acid hypersecretion in cystic fibrosis.囊性纤维化中的胃酸分泌过多
J Pediatr Gastroenterol Nutr. 1982;1(4):559-65. doi: 10.1097/00005176-198212000-00019.
3
Intraduodenal events in cystic fibrosis.囊性纤维化患者的十二指肠内情况
J Pediatr Gastroenterol Nutr. 1984;3 Suppl 1:S113-9. doi: 10.1097/00005176-198400031-00018.

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