Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Plastic and Reconstructive Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Head Neck. 2019 Nov;41(11):3755-3763. doi: 10.1002/hed.25906. Epub 2019 Aug 12.
The aims of this study were to report our center's experience with infratemporal fossa (ITF) tumors, to review the treatment modalities and outcomes.
Data of patients that underwent resection of ITF tumors in a single tertiary referral medical center were collected and analyzed.
Sixty-three patients were included. Sarcoma was the most common pathology (18; 29%). The most common surgical approach was the preauricular-orbitozygomatic approach (24; 38%), followed by endoscopic, craniofacial resection, and combined approaches. Forty-seven patients (75%) required reconstruction, 23 (49%) involving free tissue transfer. Thirty-five patients (76%) with malignant lesions required adjuvant therapy consisting of radiotherapy, chemotherapy, or both. Thirty-three patients suffered from complications related to surgery or adjuvant therapy. The three- and five-years survival rates for malignancy were 82% and 66%, respectively.
Complete surgical resection of ITF involving tumors is feasible, providing good long-term survival. Multidisciplinary approach is the key for success.
本研究旨在报告我们中心在颞下窝（ITF）肿瘤方面的经验，回顾治疗方式和结果。
收集并分析了在一家三级转诊医疗中心接受 ITF 肿瘤切除术的患者的数据。
共纳入 63 例患者。肉瘤是最常见的病理类型（18 例；29%）。最常见的手术入路是耳前-眶颧入路（24 例；38%），其次是内镜、颅面切除术和联合入路。47 例患者（75%）需要重建，其中 23 例（49%）涉及游离组织转移。35 例恶性病变患者需要辅助治疗，包括放疗、化疗或两者联合。33 例患者发生与手术或辅助治疗相关的并发症。恶性肿瘤的 3 年和 5 年生存率分别为 82%和 66%。
完全切除 ITF 肿瘤是可行的，可提供良好的长期生存。多学科方法是成功的关键。
