Department of Otolaryngology, Head and Neck Surgery, New York University, New York, NY.
Head Neck. 2013 Nov;35(11):1567-72. doi: 10.1002/hed.23186. Epub 2013 Jan 16.
A variety of tumors arise in or extend to the infratemporal fossa. We investigated the outcome of surgical management of these tumors.
We conducted a retrospective review of a craniofacial approach to resection of infratemporal fossa tumors from 1992 to 2008 in a cancer center.
Forty-three patients underwent resection of a infratemporal fossa tumors (68% men). Median age was 46 years (range, 1-81 years). The most common pathology was sarcoma (13; 30%). Twenty-two tumors (51%) were recurrent. Twenty patients (46%) underwent resection of tumors from the infratemporal fossa, 5 (12%) required resection of the anterior skull base, and 18 (42%) required orbital exenteration, additionally. Thirty-one patients (72%) required reconstruction with free tissue transfer. Twenty-seven patients (62.8%) required further treatment with radiation and/or chemotherapy. Complications occurred in 9 patients (21%). Six patients (14%) underwent salvage operations. Median follow-up was 24 months. Median overall survival and 3-year survival were 40 months and 59.6%.
Tumors involving the infratemporal fossa can be resected with acceptable morbidity and long-term survival.
多种肿瘤发生于或延伸至颞下窝。我们研究了这些肿瘤的手术治疗结果。
我们回顾性分析了 1992 年至 2008 年在癌症中心采用颅面入路切除颞下窝肿瘤的病例。
43 例患者接受了颞下窝肿瘤切除术（男性占 68%）。中位年龄为 46 岁（范围，1-81 岁）。最常见的病理类型为肉瘤（13 例；30%）。22 例肿瘤（51%）为复发性肿瘤。20 例（46%）患者接受了颞下窝肿瘤切除术，5 例（12%）患者需要切除前颅底，18 例（42%）患者需要眶内容剜除术。31 例患者（72%）需要游离组织移植进行重建。27 例患者（62.8%）需要进一步接受放疗和/或化疗。9 例患者（21%）出现并发症。6 例患者（14%）接受挽救性手术。中位随访时间为 24 个月。中位总生存期和 3 年生存率分别为 40 个月和 59.6%。
可通过手术切除累及颞下窝的肿瘤，其发病率和长期生存率可接受。
