Menezes-Rodrigues Francisco S, Scorza Cristiane S, Fiorini Ana C, Caricati-Neto Afonso, Scorza Carla A, Finsterer Josef, Scorza Fulvio A
Disciplina de Neurociência, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brasil.
Departamento de Farmacologia, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brasil.
Neurodegener Dis Manag. 2019 Aug;9(4):241-246. doi: 10.2217/nmt-2019-0010. Epub 2019 Aug 13.
Parkinson's disease (PD) is one of the most common age-related neurodegenerative disorders. Several studies over the last few years have shown that PD is accompanied by high rates of premature death compared with healthy controls. Death in PD patients is usually caused by determinant factors such as pneumonia, and cerebrovascular and cardiovascular diseases. During recent years it has emerged that dehydration may also contribute to mortality in PD. Interestingly, it has been documented that a substantial proportion of patients with PD die suddenly (known as sudden and unexpected death in PD). In this article, we focus on the magnitude of the problem of sudden and unexpected death in PD, with special reference to the daily water consumption of PD patients.
帕金森病(PD)是最常见的与年龄相关的神经退行性疾病之一。过去几年的多项研究表明,与健康对照组相比,帕金森病患者的过早死亡率较高。帕金森病患者的死亡通常由肺炎、脑血管疾病和心血管疾病等决定性因素导致。近年来发现,脱水也可能导致帕金森病患者死亡。有趣的是,有文献记载,相当一部分帕金森病患者会突然死亡(即帕金森病中的猝死和意外死亡)。在本文中,我们重点关注帕金森病中猝死和意外死亡问题的严重程度,特别提及帕金森病患者的每日饮水量。