Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Neuroscience Center of the Woman Health "Professor Geraldo Rodrigues de Lima", Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Clinics (Sao Paulo). 2022 Feb 10;77:100001. doi: 10.1016/j.clinsp.2021.100001. eCollection 2022.
Classified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies.
分类为仅次于阿尔茨海默病的与衰老相关的第二常见神经退行性疾病，帕金森病（PD）是最常见的运动障碍。在过去十年中，尽管治疗取得了进展，但与 PD 相关的死亡率仍持续达到显著水平。现有研究表明，与健康对照组相比，PD 患者的过早死亡率较高。这通常是由肺炎以及脑血管和心血管疾病等因素引起的。最近，已经证明相当一部分 PD 患者突然死亡。这被称为帕金森病的突发性意外死亡（SUDPAR）。在这里，我们重点关注 SUDPAR 的程度。最后，了解更多关于 SUDPAR 的信息对于实施有效的预防策略非常重要。
