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血小板无力症合并针对供体血小板同种抗体产生情况下的拔牙处理

The management of dental extractions in cases of thrombasthenia complicated by the development of isoantibodies to donor platelets.

作者信息

Sugar A W

出版信息

Oral Surg Oral Med Oral Pathol. 1979 Aug;48(2):116-9. doi: 10.1016/0030-4220(79)90047-1.

DOI:10.1016/0030-4220(79)90047-1
PMID:314082
Abstract

Two cases of thrombasthenia, a rare hereditary disorder of platelet function, are presented. The oral surgical and dental management of these cases is discussed in the light of the development of isoantibodies to transfused platelets in one of the cases and in another case encountered. The problems of obtaining donor platelets matched for platelet and HL-A antigens are discussed. Emphasis is placed on the use of local hemostatic measures and antifibrinolytic agents in the management of hemorrhage in this disorder and the avoidance of platelet transfusions as far as possible. Conservative dentistry and early preventive dental advice are considered desirable in order to avoid extractions.

摘要

本文介绍了两例血小板无力症,这是一种罕见的遗传性血小板功能障碍疾病。根据其中一例患者以及另一例所遇到的患者体内针对输注血小板产生同种抗体的情况,讨论了这两例患者的口腔外科和牙科治疗方法。探讨了获取与血小板和HL - A抗原相匹配的供体血小板的问题。重点强调了在该疾病出血处理中使用局部止血措施和抗纤溶药物,并尽可能避免输注血小板。为避免拔牙,认为保守牙科治疗和早期预防性牙科建议是可取的。

相似文献

1
The management of dental extractions in cases of thrombasthenia complicated by the development of isoantibodies to donor platelets.血小板无力症合并针对供体血小板同种抗体产生情况下的拔牙处理
Oral Surg Oral Med Oral Pathol. 1979 Aug;48(2):116-9. doi: 10.1016/0030-4220(79)90047-1.
2
Alloantibodies and platelet destruction.同种抗体与血小板破坏
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Management of bleeding in a multi-transfused patient with positive HLA class I alloantibodies and thrombocytopenia associated with platelet dysfunction refractory to transfusion of cross-matched platelets.对一名多次输血且伴有I类人类白细胞抗原同种抗体阳性及血小板减少症(与输注交叉配型血小板无效的血小板功能障碍相关)患者的出血管理。
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Platelet transfusions: shortened survival of HL-A-identical platelets and failure of in vitro detection of anti-platelet antibodies after multiple transfusions.血小板输注:人类白细胞抗原(HL-A)相同的血小板存活期缩短以及多次输血后体外检测抗血小板抗体失败。
Vox Sang. 1973;25(2):187-92. doi: 10.1111/j.1423-0410.1973.tb04829.x.
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[Blood platelet transfusion and homologous antibody].[血小板输注与同种抗体]
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Immunological aspects of platelet transfusions.
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Tooth extraction in a patient with Glanzmann's thrombasthenia.患有Glanzmann血小板无力症患者的拔牙术
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Serological studies in patients on platelet- and granulocyte-substitution therapy.接受血小板和粒细胞替代疗法患者的血清学研究。
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Platelet, granulocyte, and HLA antibodies in renal dialysis patients transfused with frozen blood.接受冷冻血液输血的肾透析患者体内的血小板、粒细胞和HLA抗体
Br Med J. 1980 Jul 12;281(6233):113-4. doi: 10.1136/bmj.281.6233.113-a.

引用本文的文献

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Dental Management of Seven-Year-Old Child With Glanzmann Thrombasthenia: A Case Report.患有Glanzmann血小板无力症的七岁儿童的牙科管理:一例报告
Cureus. 2024 Sep 26;16(9):e70243. doi: 10.7759/cureus.70243. eCollection 2024 Sep.
2
Glanzmann's Thrombastenia: The Role of Tranexamic Acid in Oral Surgery.血小板无力症:氨甲环酸在口腔外科手术中的作用
Case Rep Dent. 2018 Sep 5;2018:9370212. doi: 10.1155/2018/9370212. eCollection 2018.