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Checkpoint Inhibitor-Induced Rejection of a Liver Allograft: A Combination of Acute T Cell-Mediated and Antibody-Mediated Rejection.

作者信息

Lee Brian T, Horwich Brian H, Chopra Shefali, Ahearn Aaron, Han Hyosun H

机构信息

Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

出版信息

Liver Transpl. 2019 Dec;25(12):1845-1848. doi: 10.1002/lt.25622. Epub 2019 Sep 25.

DOI:10.1002/lt.25622
PMID:31408574
Abstract
摘要

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2
Immune suppression sustained allograft acceptance requires PD1 inhibition of CD8+ T cells.维持同种异体移植物接受的免疫抑制需要PD1抑制CD8 + T细胞。
J Immunol. 2025 Jan 1;214(1):192-198. doi: 10.1093/jimmun/vkae007.
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Pretransplant immunotherapy increases acute rejection yet improves survival outcome of HCC patients with MVI post-liver transplantation.
移植前免疫治疗增加了 HCC 患者肝移植后 MVI 的急性排斥反应，但改善了生存结局。
Cancer Immunol Immunother. 2024 Nov 11;74(1):18. doi: 10.1007/s00262-024-03853-9.
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Cancers (Basel). 2024 Jun 28;16(13):2374. doi: 10.3390/cancers16132374.
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Front Immunol. 2021 Jul 19;12:653437. doi: 10.3389/fimmu.2021.653437. eCollection 2021.